{"id":"W2142982089","doi":"10.15252/emmm.201303541","title":"Epidermal p65/NF‐κB signalling is essential for skin carcinogenesis","year":2014,"lang":"en","type":"article","venue":"EMBO Molecular Medicine","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Partenariat Canadien Contre Le Cancer; Deutsche Krebshilfe; Deutsche Forschungsgemeinschaft; European Commission","keywords":"Proinflammatory cytokine; Carcinogenesis; DMBA; Keratinocyte; Chemokine; Cancer research; Chemistry; DNA damage; Inflammation; Cell biology; Biology; Immunology; In vitro; DNA; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006894185,0.0003464402,0.0004205211,0.0001035534,0.0001377504,0.0000172549,0.0003708931,0.000251863,0.0001157866],"category_scores_gemma":[0.0004225281,0.0003228222,0.0002519166,0.0001382399,0.0001764213,0.00000394994,0.000110358,0.0001245545,0.0000201978],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001837288,"about_ca_system_score_gemma":0.00008000957,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007024478,"about_ca_topic_score_gemma":0.000009226921,"domain_scores_codex":[0.9977547,0.0001432894,0.000452251,0.0007347595,0.0003713134,0.0005437146],"domain_scores_gemma":[0.9987075,0.00006006841,0.0001649123,0.0006223769,0.000215785,0.0002293882],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006857519,0.00003832292,0.0001620722,0.00007063474,0.0001170678,0.00001122413,0.0001367084,0.0002578743,0.9926674,0.0004251134,0.004274017,0.001771029],"study_design_scores_gemma":[0.001716753,0.0005976773,0.0001198314,0.00006379896,0.0001547216,0.00002941525,0.00004430113,0.001242687,0.9613695,0.0004928567,0.03380949,0.0003589678],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6692804,0.001786878,0.3254194,0.001354975,0.000437035,0.0004215985,0.00002249104,0.00003902133,0.001238261],"genre_scores_gemma":[0.9903173,0.00003858605,0.002865338,0.004160148,0.001755376,0.00007308596,0.0003161529,0.00009517028,0.000378797],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3225541,"threshold_uncertainty_score":0.9999224,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01095703610147975,"score_gpt":0.2601732032854866,"score_spread":0.2492161671840069,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}