{"id":"W2142991019","doi":"10.1016/j.stemcr.2013.04.003","title":"The Luminal Progenitor Compartment of the Normal Human Mammary Gland Constitutes a Unique Site of Telomere Dysfunction","year":2013,"lang":"en","type":"article","venue":"Stem Cell Reports","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"National Cancer Institute; Canadian Breast Cancer Research Alliance; Ralph W. and Grace M. Showalter Research Trust Fund; Flight Attendant Medical Research Institute; Terry Fox Foundation; Eli Lilly and Company; Susan G. Komen for the Cure; Lilly Endowment; Avon Foundation for Women","keywords":"Biology; Telomere; Compartment (ship); Progenitor; Progenitor cell; Mammary gland; Cell biology; Gene; Genetics; Stem cell; Cancer; Breast cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002858462,0.0001630929,0.0003164503,0.00004935412,0.000206303,0.00002125711,0.0001017659,0.00007330997,0.00004226543],"category_scores_gemma":[0.00001642923,0.00009020562,0.0001404504,0.000173615,0.0003378861,0.00009416004,0.00008040018,0.0001562755,0.000006344488],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004233795,"about_ca_system_score_gemma":0.0002310228,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003446174,"about_ca_topic_score_gemma":0.00006933636,"domain_scores_codex":[0.9983637,0.00007432301,0.0006825055,0.0002278178,0.0004195728,0.0002320629],"domain_scores_gemma":[0.9983119,0.00006636887,0.0005680935,0.0006806798,0.0002720915,0.000100815],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009656225,0.0003581226,0.7573335,0.0006129696,0.0001258703,0.0002265859,0.0007180017,0.000005974501,0.230387,0.0003072959,0.004687376,0.005140722],"study_design_scores_gemma":[0.0008487713,0.0004245878,0.3911354,0.0003101878,0.0001893959,0.001220608,0.0007618257,0.00004096975,0.585511,0.0001097459,0.01923023,0.0002172706],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915897,0.0006875469,0.00002371112,0.0002107531,0.0005252917,0.00109478,0.000004366872,0.00003031039,0.005833506],"genre_scores_gemma":[0.9964086,0.00003779491,0.00009118687,0.00003952066,0.0001075239,0.00005578753,0.00001404725,0.00001212154,0.00323342],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3661982,"threshold_uncertainty_score":0.3678478,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009443838497366392,"score_gpt":0.2193414805294928,"score_spread":0.2098976420321264,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}