{"id":"W2143006986","doi":"10.1634/theoncologist.2010-0263","title":"Sunitinib in Metastatic Renal Cell Carcinoma: Recommendations for Management of Noncardiovascular Toxicities","year":2011,"lang":"en","type":"review","venue":"The Oncologist","topic":"Renal cell carcinoma treatment","field":"Medicine","cited_by":81,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre; BC Cancer Agency","funders":"Genentech; GlaxoSmithKline; Pfizer","keywords":"Sunitinib; Medicine; Dosing; Renal cell carcinoma; Intensive care medicine; Tyrosine-kinase inhibitor; Toxicity; Oncology; Internal medicine; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00105988,0.0004114517,0.002184271,0.000244664,0.00007358802,0.00001046873,0.0003486465,0.0001366302,0.000113701],"category_scores_gemma":[0.00002671686,0.0002482368,0.001194898,0.0003179247,0.0002263185,0.00002758158,0.0001449614,0.0003020969,0.00003083713],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005490051,"about_ca_system_score_gemma":0.0002973305,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002074095,"about_ca_topic_score_gemma":0.0000326652,"domain_scores_codex":[0.9977276,0.0004139904,0.0009245243,0.000373772,0.0002124031,0.0003477269],"domain_scores_gemma":[0.9979677,0.0004773075,0.0004986934,0.0008939282,0.00008934027,0.00007303272],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001538131,0.0008669683,0.00001190673,0.05202775,0.002112803,0.0004222128,0.0003633979,0.000002818376,0.000001070834,0.001656135,0.00394697,0.9384342],"study_design_scores_gemma":[0.001753129,0.0008860298,0.0001032137,0.004420579,0.01170849,0.0001189458,0.0005671959,0.000001697611,0.00006891748,0.0001511128,0.9799892,0.0002315481],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002228863,0.9690383,0.0001160767,0.0001173989,0.0001665019,0.004404604,0.0001603473,0.00002088628,0.02575298],"genre_scores_gemma":[0.001481217,0.9868333,0.005782584,0.00003744124,0.00008073154,0.001854928,0.0004905438,0.00006315984,0.003376102],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9760422,"threshold_uncertainty_score":0.999997,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2058973565908037,"score_gpt":0.3785723291003016,"score_spread":0.1726749725094979,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}