{"id":"W2143008582","doi":"10.1634/theoncologist.2013-0390","title":"Diagnostic Value of Next-Generation Sequencing in an Unusual Sphenoid Tumor","year":2014,"lang":"en","type":"article","venue":"The Oncologist","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Canada's Michael Smith Genome Sciences Centre; BC Cancer Agency","funders":"Terry Fox Research Institute; Canada Research Chairs; Genome British Columbia; Genome Canada","keywords":"Transcriptome; Medicine; DNA sequencing; Genome; Precision medicine; Cancer; Personalized medicine; SMARCB1; Computational biology; Oncology; Bioinformatics; Genetics; Pathology; Internal medicine; Gene; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004035365,0.00007242568,0.000100288,0.00001260521,0.0000447268,0.00001265262,0.0001534368,0.00005511267,0.000006152055],"category_scores_gemma":[0.000343338,0.00005292664,0.00002895161,0.0000494061,0.00009290185,0.000003128167,0.00003911196,0.00005882548,0.000002781013],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005704828,"about_ca_system_score_gemma":0.0001212945,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003289671,"about_ca_topic_score_gemma":0.0007974966,"domain_scores_codex":[0.9993479,0.0001429902,0.0001671925,0.0001546912,0.00006997758,0.0001173033],"domain_scores_gemma":[0.9995721,0.00005101004,0.00007637157,0.0002415216,0.00003488526,0.00002411],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001964743,0.00003103075,0.001562873,0.00001096881,0.00000458553,0.000001044647,0.00009810509,0.03244934,0.960567,0.0003614874,0.0001871288,0.00470682],"study_design_scores_gemma":[0.001077095,0.001639454,0.008470537,0.00005055646,0.00003770005,0.0000230907,0.0005689612,0.1846786,0.8002393,0.00095089,0.00194143,0.0003224635],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968294,0.0002125258,0.001844326,0.00008337742,0.0001120561,0.00009661446,0.000002965035,0.000007081406,0.0008116525],"genre_scores_gemma":[0.9985682,0.00003116683,0.0006162667,0.0003062986,0.0003697096,0.00001539622,0.00003462093,0.000008813232,0.00004946564],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1603277,"threshold_uncertainty_score":0.2158286,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05352112794267109,"score_gpt":0.2999288822729578,"score_spread":0.2464077543302867,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}