{"id":"W2143086018","doi":"10.1161/hc4701.100513","title":"Phospholipid Metabolite 1-Palmitoyl-Lysophosphatidylcholine Enhances Human <i>Ether-a-Go-Go</i> -Related Gene (HERG) K <sup>+</sup> Channel Function","year":2001,"lang":"en","type":"article","venue":"Circulation","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; McGill University","funders":"Canadian Institutes of Health Research; Heart And Stroke Foundation Of Quebec; Heart and Stroke Foundation of Canada","keywords":"hERG; Lysophosphatidylcholine; Patch clamp; Electrophysiology; Medicine; Metabolite; Depolarization; Voltage clamp; Pharmacology; Phospholipid; Potassium channel; Biophysics; Internal medicine; Chemistry; Biology; Biochemistry; Phosphatidylcholine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001202696,0.0003152208,0.0002404766,0.00008620485,0.00007054536,0.0002280355,0.0001586876,0.0002633832,0.001144804],"category_scores_gemma":[0.0002296431,0.00005705207,0.0002242846,0.00008751051,0.0002295014,0.0002302541,0.0001736065,0.000392121,0.0003118154],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002517584,"about_ca_system_score_gemma":0.0001486565,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003298268,"about_ca_topic_score_gemma":0.0004326488,"domain_scores_codex":[0.999916,0.00001536817,0.00001112932,0.00001732375,0.00001673976,0.00002352693],"domain_scores_gemma":[0.999897,0.0000358024,0.00002541966,0.000008206072,0.00001501291,0.00001852458],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002382764,0.00001961819,0.0001298529,0.00004156738,0.000003777673,0.00003690196,0.000008884073,0.00002014727,0.9987144,0.00001766093,0.00001849403,0.0007503179],"study_design_scores_gemma":[0.0000162366,0.0003108536,0.001973096,0.000003783039,0.0000146912,0.0001249548,0.00001312486,0.0001968923,0.9968643,0.000009164649,0.0004711199,0.000001600188],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996798,0.001234475,0.0009432701,0.000122453,0.00001682273,0.00002182107,0.0001851068,0.00004708791,0.0006309805],"genre_scores_gemma":[0.9968715,0.0008594212,0.001187691,0.0001058232,0.000009725532,0.0000236803,0.0002583999,0.00001726876,0.0006664468],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001144804,"threshold_uncertainty_score":0.003829718,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01220679455526678,"score_gpt":0.2501827505756313,"score_spread":0.2379759560203645,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}