{"id":"W2143137932","doi":"10.1242/dev.02277","title":"Ets2 is necessary in trophoblast for normal embryonic anteroposterior axis development","year":2006,"lang":"en","type":"article","venue":"Development","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":80,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"","keywords":"Epiblast; Primitive streak; Biology; Phenocopy; Trophoblast; Cell biology; Mesoderm; Endoderm; Genetics; Ectoderm; Embryonic stem cell; Embryogenesis; Mutant; Embryo; Gastrulation; Placenta; Gene; Fetus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001039125,0.0003384947,0.0001667623,0.0002089231,0.0002346881,0.0003467724,0.0001815238,0.0002465206,0.001976868],"category_scores_gemma":[0.0001758374,0.0002335759,0.0001537793,0.000133587,0.0002642683,0.0002390059,0.0004081167,0.0003045787,0.001026447],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002452453,"about_ca_system_score_gemma":0.0002814265,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006111032,"about_ca_topic_score_gemma":0.0009148202,"domain_scores_codex":[0.999864,0.00001622384,0.00001538896,0.00003383475,0.00005114676,0.00001937604],"domain_scores_gemma":[0.999899,0.00001748511,0.00002642776,0.00001350872,0.0000109054,0.00003262502],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004178393,0.000004235167,0.0003030111,0.00001947874,0.000002012488,0.0001332534,0.00000898497,0.000039029,0.9985988,0.0001567182,0.00003173299,0.0006611078],"study_design_scores_gemma":[0.00002871718,0.00008689777,0.02495098,0.00001138035,0.00001613455,0.001426422,0.00005176117,0.0009944795,0.9605893,0.0002950752,0.01153821,0.00001053808],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9780546,0.003018894,0.0101284,0.0002629315,0.00006869341,0.00002739634,0.00163662,0.0003018503,0.006500585],"genre_scores_gemma":[0.9860805,0.00110454,0.003667566,0.00005620853,0.00001923296,0.0000290156,0.002376465,0.00007260222,0.006593867],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001976868,"threshold_uncertainty_score":0.006613314,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0105316551161642,"score_gpt":0.2486732133856899,"score_spread":0.2381415582695257,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}