{"id":"W2143137932","doi":"10.1242/dev.02277","title":"Ets2 is necessary in trophoblast for normal embryonic anteroposterior axis development","year":2006,"lang":"en","type":"article","venue":"Development","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":80,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"","keywords":"Epiblast; Primitive streak; Biology; Phenocopy; Trophoblast; Cell biology; Mesoderm; Endoderm; Genetics; Ectoderm; Embryonic stem cell; Embryogenesis; Mutant; Embryo; Gastrulation; Placenta; Gene; Fetus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002882549,0.0002367099,0.0002013038,0.0001388336,0.0001305328,0.00004206668,0.000303986,0.0001480769,0.00005294612],"category_scores_gemma":[0.00001244421,0.0002352278,0.00006289075,0.0001327286,0.00004243396,0.000007173813,0.0002660529,0.00009266816,0.00007935845],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001389543,"about_ca_system_score_gemma":0.0005063461,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002279776,"about_ca_topic_score_gemma":0.0003183705,"domain_scores_codex":[0.9981258,0.00003450059,0.0004380258,0.0005193305,0.0002743516,0.000608003],"domain_scores_gemma":[0.999499,0.000009363222,0.00007449182,0.0002419204,0.00008906255,0.00008614099],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006455088,0.0005029129,0.02609154,0.0003035913,0.0001268608,0.00005167902,0.0006275587,0.00006613998,0.9165928,0.00001559568,0.02577473,0.02920113],"study_design_scores_gemma":[0.001149205,0.00009497887,0.07711563,0.00004055657,0.000002366653,0.00001221516,0.00005635127,0.00003334729,0.5925215,0.000006668568,0.3286628,0.0003043158],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950529,0.0004573481,0.002403641,0.0003442723,0.0001379516,0.0005395645,0.00001495453,0.0000142786,0.001035127],"genre_scores_gemma":[0.9672827,0.00005099373,0.01914885,0.0003490187,0.0001164314,0.0003205038,0.0004750152,0.00004866717,0.01220786],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3240712,"threshold_uncertainty_score":0.9592312,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0105316551161642,"score_gpt":0.2486732133856899,"score_spread":0.2381415582695257,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}