{"id":"W2143149828","doi":"10.1093/cercor/bht364","title":"Transient Maternal Hypothyroxinemia Potentiates the Transcriptional Response to Exogenous Thyroid Hormone in the Fetal Cerebral Cortex Before the Onset of Fetal Thyroid Function: A Messenger and MicroRNA Profiling Study","year":2014,"lang":"en","type":"article","venue":"Cerebral Cortex","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada","funders":"","keywords":"Fetus; Thyroid; Endocrinology; Internal medicine; Hormone; Microarray; Gene expression; Cerebral cortex; microRNA; Thyroid function; Biology; Gene; Medicine; Pregnancy; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001486216,0.00021873,0.0002930966,0.0002911318,0.0001459394,0.0002635178,0.0001536043,0.0001494117,0.0008097377],"category_scores_gemma":[0.0001391707,0.0001631853,0.0002695586,0.000139877,0.0003289099,0.0001466125,0.0001916033,0.0004657262,0.0001817212],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004038075,"about_ca_system_score_gemma":0.0004284618,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001463018,"about_ca_topic_score_gemma":0.002980504,"domain_scores_codex":[0.9998611,0.00001015991,0.000008933379,0.00004121454,0.00004042447,0.00003817419],"domain_scores_gemma":[0.9999039,0.00001960101,0.00002992673,0.00000958341,0.0000147635,0.00002218505],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001301778,0.000006389814,0.0002159751,0.0000142177,0.000002877128,0.00003891858,0.00001775363,0.000009860833,0.9989958,0.00003310731,0.00001011211,0.0005247779],"study_design_scores_gemma":[0.00001756367,0.0002259554,0.02701087,0.000006830294,0.00003305824,0.0002731812,0.00009485715,0.0003259877,0.9709784,0.00005559319,0.0009713019,0.000006243627],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953119,0.001563935,0.00183684,0.0000951265,0.00002205904,0.00001403825,0.00032486,0.00003483485,0.0007963628],"genre_scores_gemma":[0.9926801,0.001517716,0.002708397,0.00009275995,0.00001527717,0.0000580802,0.000500182,0.00002914485,0.002398501],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001463018,"threshold_uncertainty_score":0.002929807,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01024210715174742,"score_gpt":0.232789995902369,"score_spread":0.2225478887506216,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}