{"id":"W2143157762","doi":"10.1038/sj.emboj.7601531","title":"Structural basis of T‐cell specificity and activation by the bacterial superantigen TSST‐1","year":2007,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":61,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"National Institute of General Medical Sciences; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Superantigen; T-cell receptor; Biology; Major histocompatibility complex; Cell biology; Receptor; T cell; Molecular biology; Immunology; Antigen; Genetics; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005697593,0.00008260248,0.0001050853,0.00003757108,0.0004099267,0.00002944935,0.0001289279,0.00006657943,0.002520904],"category_scores_gemma":[0.00003097978,0.00004297786,0.00005725394,0.00005279881,0.0001336935,0.0001279189,0.00002538649,0.0003969344,0.00002964131],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002320952,"about_ca_system_score_gemma":0.00001525535,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005705903,"about_ca_topic_score_gemma":0.00000492466,"domain_scores_codex":[0.9993253,0.0001650983,0.0002496586,0.00007031411,0.00003713517,0.0001524559],"domain_scores_gemma":[0.9994914,0.0001523702,0.0001669711,0.0001105248,0.00006807688,0.00001068095],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004929881,0.00001576285,0.0004453152,0.000001889963,0.00004687714,2.388813e-7,0.0007062206,9.718682e-7,0.9839575,0.0000688053,0.01073013,0.003533324],"study_design_scores_gemma":[0.0006420666,0.00009252543,0.02000567,0.000007733268,0.00002276932,0.0003300504,0.001356496,0.000003949025,0.9446527,0.00007885979,0.03274836,0.0000588147],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994329,0.0003869384,0.0004278916,0.0004409951,0.0027507,0.00007274307,0.000002328829,0.000006726119,0.001582649],"genre_scores_gemma":[0.9969108,0.00009424081,0.00001017064,0.0001197841,0.0001589836,3.665376e-7,0.00001388015,0.000005947196,0.002685895],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03930478,"threshold_uncertainty_score":0.9983909,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0123628896254903,"score_gpt":0.2239232728578514,"score_spread":0.2115603832323611,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}