{"id":"W2143166786","doi":"10.1016/j.clinbiochem.2003.11.012","title":"Altered kallikrein 7 and 10 concentrations in cerebrospinal fluid of patients with Alzheimer's disease and frontotemporal dementia","year":2003,"lang":"en","type":"article","venue":"Clinical Biochemistry","topic":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Mount Sinai Hospital","funders":"","keywords":"Kallikrein; Cerebrospinal fluid; Frontotemporal dementia; Proteases; Internal medicine; Pathogenesis; Alzheimer's disease; Dementia; Endocrinology; Disease; Medicine; Pathology; Gastroenterology; Biology; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001337091,0.0001245607,0.0002676123,0.00001593886,0.00003508865,0.00001102144,0.00003460686,0.00009050804,0.0001595546],"category_scores_gemma":[0.0002136288,0.0001070892,0.00004924912,0.00006272395,0.0002871977,0.00004592798,0.00001993375,0.00008901349,0.00000133624],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008645812,"about_ca_system_score_gemma":0.0001448783,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000118043,"about_ca_topic_score_gemma":0.000004934077,"domain_scores_codex":[0.9989139,0.00003084179,0.0004638798,0.0003018766,0.0001387941,0.0001507201],"domain_scores_gemma":[0.9992542,0.00006959254,0.0001220671,0.0001949063,0.00007833276,0.0002809559],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004269385,0.0003279306,0.9977216,0.00005333617,0.0001013017,0.000003624632,0.00001912728,3.552395e-7,0.0003026731,0.00006699867,0.0003297074,0.0006464187],"study_design_scores_gemma":[0.003987735,0.0002299433,0.9905494,0.0001254569,0.0003047505,0.000001302739,0.00002741095,0.00008360297,0.004118527,0.00008478873,0.0003630332,0.0001240064],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995497,0.003806986,0.0000192145,0.0001497694,0.00004312434,0.0002069552,0.00003491768,0.00001105718,0.0002310139],"genre_scores_gemma":[0.998947,0.00008309654,0.0005410663,0.0001163681,0.00005490215,0.00000620884,0.0001483891,0.00001003344,0.00009299212],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007172145,"threshold_uncertainty_score":0.4366969,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02282743057696016,"score_gpt":0.2964298658730543,"score_spread":0.2736024352960941,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}