{"id":"W2143197414","doi":"10.1016/j.vph.2008.09.001","title":"Effects of bone morphogenic proteins and transforming growth factor-beta on In-vitro production of endothelin-1 by human pulmonary microvascular endothelial cells","year":2008,"lang":"en","type":"article","venue":"Vascular Pharmacology","topic":"Pulmonary Hypertension Research and Treatments","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Fonds de Recherche du Québec - Santé; Jewish General Hospital","keywords":"SMAD; Bone morphogenetic protein; Endothelin 1; Transforming growth factor; Bone morphogenetic protein 2; Internal medicine; Biology; Endocrinology; Receptor; Endothelin receptor; BMPR2; Transforming growth factor beta; Bone morphogenetic protein 4; Cell biology; In vitro; Chemistry; Medicine; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000951289,0.0005780413,0.0006933404,0.000433904,0.0003739123,0.0005015597,0.0004933402,0.0005305394,0.001794351],"category_scores_gemma":[0.000967455,0.0003825728,0.0008087823,0.0004866252,0.0006032875,0.0005535363,0.0003780159,0.001243056,0.0004449422],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003448909,"about_ca_system_score_gemma":0.0003545553,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002110714,"about_ca_topic_score_gemma":0.001815987,"domain_scores_codex":[0.9991454,0.0003799689,0.00007312342,0.00006038119,0.0001165633,0.0002245077],"domain_scores_gemma":[0.998654,0.0008960814,0.00006759763,0.0001472293,0.00009193758,0.00014311],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00853507,0.001155869,0.001188867,0.0001717488,0.00005945837,0.0007426696,0.0003205488,0.0003847177,0.9828886,0.0002541863,0.0002481026,0.00405023],"study_design_scores_gemma":[0.0003958761,0.004527132,0.01470222,0.00002008989,0.0001228608,0.0005041842,0.0001878372,0.00178566,0.9756755,0.0001696908,0.001891165,0.00001781399],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938745,0.002438522,0.00119466,0.0001811827,0.0001291475,0.00004717615,0.0003999328,0.00002955676,0.001705295],"genre_scores_gemma":[0.9928824,0.001661197,0.001760329,0.0001820965,0.0001388533,0.0000728281,0.001330306,0.00002022325,0.001951764],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002110714,"threshold_uncertainty_score":0.006002665,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01286538243393843,"score_gpt":0.257691844105863,"score_spread":0.2448264616719246,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}