{"id":"W2143256071","doi":"10.1128/iai.00318-08","title":"Human Host Defense Peptide LL-37 Prevents Bacterial Biofilm Formation","year":2008,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":682,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Alexander von Humboldt-Stiftung","keywords":"Biofilm; Microbiology; Biology; Quorum sensing; Pseudomonas aeruginosa; Innate immune system; Peptide; Bacteria; Antimicrobial peptides; Polymyxin B; Cathelicidin; In vitro; Polymyxin; Antimicrobial; Immune system; Biochemistry; Immunology; Antibiotics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001225563,0.0001389146,0.0001703988,0.00007319016,0.0009703051,0.00002474723,0.00005363619,0.0001651167,0.0005788806],"category_scores_gemma":[0.00002476329,0.000131058,0.00007317147,0.00006792602,0.0002376856,0.0004071782,0.00007305883,0.0002610809,0.000182462],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000296151,"about_ca_system_score_gemma":0.00001729344,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00148683,"about_ca_topic_score_gemma":0.00009825918,"domain_scores_codex":[0.9992768,0.0001791436,0.0002074259,0.0001217866,0.00001900027,0.0001958253],"domain_scores_gemma":[0.9996529,0.00002469295,0.0001118606,0.0001514201,0.00004095199,0.00001820554],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006438093,0.0001506311,0.006164209,0.00002014766,0.00005175199,0.000001348026,0.0006297521,7.924804e-7,0.9867136,0.0001622618,0.005230444,0.0008107062],"study_design_scores_gemma":[0.00239828,0.0005392989,0.4234247,0.00007206821,0.00005207496,0.0009099853,0.0002770921,0.000003187077,0.515429,0.0001243709,0.05632761,0.0004423594],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959213,0.0000990163,0.00008315168,0.0000302901,0.0005248345,0.0001453006,0.00002346838,0.00009509637,0.003077583],"genre_scores_gemma":[0.9964018,0.0003184184,0.00001996167,0.0000897377,0.00005106428,0.000007449485,0.0001698962,0.000009964088,0.002931712],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4712846,"threshold_uncertainty_score":0.74629,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02024297527937697,"score_gpt":0.2380634379196654,"score_spread":0.2178204626402885,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}