{"id":"W2143256071","doi":"10.1128/iai.00318-08","title":"Human Host Defense Peptide LL-37 Prevents Bacterial Biofilm Formation","year":2008,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":682,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Alexander von Humboldt-Stiftung","keywords":"Biofilm; Microbiology; Biology; Quorum sensing; Pseudomonas aeruginosa; Innate immune system; Peptide; Bacteria; Antimicrobial peptides; Polymyxin B; Cathelicidin; In vitro; Polymyxin; Antimicrobial; Immune system; Biochemistry; Immunology; Antibiotics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001960144,0.000318499,0.000294159,0.0001104432,0.00008809426,0.0002867045,0.0001567992,0.0001820206,0.001008987],"category_scores_gemma":[0.0003254963,0.00008443234,0.0001186479,0.00005550735,0.0003812837,0.0001470242,0.0002624502,0.0003740305,0.000327758],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002195423,"about_ca_system_score_gemma":0.0003130268,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004916312,"about_ca_topic_score_gemma":0.0005613741,"domain_scores_codex":[0.9998288,0.00004828948,0.00001105561,0.00002463442,0.00004455845,0.00004255716],"domain_scores_gemma":[0.9998515,0.0000464451,0.00003130841,0.00001635949,0.00001375023,0.00004065124],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003729369,0.00004183079,0.0002044155,0.00004630848,0.000004526567,0.00003935111,0.00001390834,0.00006385744,0.9949374,0.00003259927,0.00006243372,0.004180467],"study_design_scores_gemma":[0.00003807442,0.001851361,0.002729446,0.00001121077,0.00001634562,0.0003903006,0.00002521702,0.0004595835,0.9914351,0.00005137393,0.002987273,0.000004772704],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930161,0.00430971,0.001633947,0.0001047512,0.00003021701,0.0000204679,0.00009576682,0.00007417144,0.0007148528],"genre_scores_gemma":[0.996179,0.0009967124,0.001475438,0.00006352129,0.00001422443,0.00001411927,0.0001878935,0.00001564783,0.001053317],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001008987,"threshold_uncertainty_score":0.003375411,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02024297527937697,"score_gpt":0.2380634379196654,"score_spread":0.2178204626402885,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}