{"id":"W2143265231","doi":"10.1056/nejmoa0807252","title":"Effect of Early versus Deferred Antiretroviral Therapy for HIV on Survival","year":2009,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"HIV/AIDS Research and Interventions","field":"Medicine","cited_by":1109,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; University of Toronto; AIDS Vancouver; University of Calgary; Simon Fraser University","funders":"National Center for Research Resources; National Institute of Allergy and Infectious Diseases; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Agency for Healthcare Research and Quality; National Institutes of Health; Gilead Sciences; GlaxoSmithKline; National Institute on Alcohol Abuse and Alcoholism; Kaiser Permanente; Ontario HIV Treatment Network; Johns Hopkins University; National Institute of Mental Health; Pfizer; National Institute on Aging; National Institute on Drug Abuse; Bristol-Myers Squibb","keywords":"Medicine; Antiretroviral therapy; Asymptomatic; Internal medicine; Cohort; Confidence interval; Human immunodeficiency virus (HIV); Relative risk; Surgery; Viral load; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00150018,0.0001320868,0.0006010889,0.0002883518,0.0000346957,0.000006007573,0.0001270073,0.00005637823,0.0001782951],"category_scores_gemma":[0.001419103,0.00007403292,0.0002647843,0.0001560726,0.00007377419,0.00006454396,0.000004608762,0.0003203665,0.00000435172],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003417879,"about_ca_system_score_gemma":0.0001049058,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003005776,"about_ca_topic_score_gemma":0.000003214153,"domain_scores_codex":[0.9984463,0.0001683096,0.0004678513,0.0000981736,0.0005964194,0.0002229217],"domain_scores_gemma":[0.9983695,0.0007288651,0.0002081012,0.0001513384,0.0002279155,0.0003143531],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.09436612,0.0002122023,0.005656319,0.0000631212,0.0002608251,0.00008401785,0.0003115037,0.000002329056,0.01769972,0.0002152166,0.05057607,0.8305526],"study_design_scores_gemma":[0.2628443,0.6899107,0.01233208,0.001127207,0.0002153476,0.0001155829,0.00005876223,0.00009023464,0.009453648,0.0001538386,0.02360622,0.00009211657],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.987126,0.001064549,0.000896778,0.005738329,0.0003919244,0.0003105694,0.000006745869,0.000008425674,0.004456704],"genre_scores_gemma":[0.9941984,0.0003244404,0.0001213545,0.00008269855,0.002625752,0.000001119561,0.0000104779,0.00001172529,0.002624067],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8304604,"threshold_uncertainty_score":0.3018975,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03705791233731866,"score_gpt":0.3763923650000684,"score_spread":0.3393344526627498,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}