{"id":"W2143265231","doi":"10.1056/nejmoa0807252","title":"Effect of Early versus Deferred Antiretroviral Therapy for HIV on Survival","year":2009,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"HIV/AIDS Research and Interventions","field":"Medicine","cited_by":1109,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; University of Toronto; AIDS Vancouver; University of Calgary; Simon Fraser University","funders":"National Center for Research Resources; National Institute of Allergy and Infectious Diseases; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Agency for Healthcare Research and Quality; National Institutes of Health; Gilead Sciences; GlaxoSmithKline; National Institute on Alcohol Abuse and Alcoholism; Kaiser Permanente; Ontario HIV Treatment Network; Johns Hopkins University; National Institute of Mental Health; Pfizer; National Institute on Aging; National Institute on Drug Abuse; Bristol-Myers Squibb","keywords":"Medicine; Antiretroviral therapy; Asymptomatic; Internal medicine; Cohort; Confidence interval; Human immunodeficiency virus (HIV); Relative risk; Surgery; Viral load; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01082162,0.0004277579,0.0007039373,0.0004299435,0.000220893,0.0008404299,0.0006731707,0.000663346,0.0009493898],"category_scores_gemma":[0.01943567,0.0001487891,0.001334176,0.0002509608,0.0005144959,0.0005405034,0.0005345718,0.001247012,0.00005759274],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005086758,"about_ca_system_score_gemma":0.0009043611,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009896825,"about_ca_topic_score_gemma":0.001302383,"domain_scores_codex":[0.9947888,0.003650788,0.0001698093,0.0004128116,0.000481655,0.0004960608],"domain_scores_gemma":[0.9647347,0.02715223,0.003465207,0.00100814,0.0006084734,0.003031111],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.1660064,0.00122463,0.7234463,0.0006121458,0.004672675,0.0005150755,0.0003240754,0.005372664,0.001792669,0.0005907798,0.0005810119,0.09486157],"study_design_scores_gemma":[0.006100337,0.06689735,0.903236,0.0003344284,0.005720256,0.001203134,0.0002945743,0.01140681,0.001914344,0.001105788,0.001719348,0.00006772954],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933553,0.005514936,0.000307084,0.0002277928,0.00004599116,0.0000260256,0.00006971232,0.000007235187,0.0004459209],"genre_scores_gemma":[0.9992137,0.0003335845,0.0001795583,0.00008958831,0.0000452764,0.00001063117,0.00004686593,0.000001930663,0.00007884358],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01082162,"threshold_uncertainty_score":0.05723089,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03705791233731866,"score_gpt":0.3763923650000684,"score_spread":0.3393344526627498,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}