{"id":"W2143274699","doi":"10.1200/jco.2009.27.4449","title":"Tirapazamine, Cisplatin, and Radiation Versus Cisplatin and Radiation for Advanced Squamous Cell Carcinoma of the Head and Neck (TROG 02.02, HeadSTART): A Phase III Trial of the Trans-Tasman Radiation Oncology Group","year":2010,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Head and Neck Cancer Studies","field":"Medicine","cited_by":374,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"American Society of Clinical Oncology; Sanofi","keywords":"Tirapazamine; Medicine; Radiation therapy; Cisplatin; Head and neck cancer; Hazard ratio; Head and neck squamous-cell carcinoma; Urology; Larynx; Oncology; Chemotherapy; Internal medicine; Surgery; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002062576,0.0001791106,0.001442561,0.0001032483,0.0001375757,0.000006390824,0.0001120669,0.0004221167,0.00001022707],"category_scores_gemma":[0.002608734,0.0001114527,0.0002995475,0.0001531054,0.000464626,0.0001318066,0.00003497747,0.0007372702,1.098243e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008603553,"about_ca_system_score_gemma":0.0006923284,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004163363,"about_ca_topic_score_gemma":0.0004669883,"domain_scores_codex":[0.9968607,0.0004173084,0.001985422,0.00023531,0.0002774378,0.0002237654],"domain_scores_gemma":[0.9928415,0.00438011,0.002139608,0.0001990076,0.0002416438,0.0001981643],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.2044121,0.002399505,0.02573454,0.0002022966,0.0001837979,0.000008566346,0.002006255,0.00001287772,0.01416254,0.0002319539,0.001211507,0.7494341],"study_design_scores_gemma":[0.5496914,0.09852203,0.3113752,0.00007156616,0.001149262,0.00008174201,0.0004188375,0.001541322,0.00352449,0.0001907191,0.03326065,0.000172777],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9879817,0.00154767,0.0000819038,0.006073546,0.002721359,0.001209405,0.00002826411,0.000004022457,0.0003520859],"genre_scores_gemma":[0.996531,0.001069473,0.000927458,0.0003981971,0.0009994508,0.00002233395,0.000006188582,0.00001641295,0.00002948279],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7492613,"threshold_uncertainty_score":0.4544908,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06176604674376193,"score_gpt":0.4350159016102489,"score_spread":0.373249854866487,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}