{"id":"W2143274699","doi":"10.1200/jco.2009.27.4449","title":"Tirapazamine, Cisplatin, and Radiation Versus Cisplatin and Radiation for Advanced Squamous Cell Carcinoma of the Head and Neck (TROG 02.02, HeadSTART): A Phase III Trial of the Trans-Tasman Radiation Oncology Group","year":2010,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Head and Neck Cancer Studies","field":"Medicine","cited_by":374,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"American Society of Clinical Oncology; Sanofi","keywords":"Tirapazamine; Medicine; Radiation therapy; Cisplatin; Head and neck cancer; Hazard ratio; Head and neck squamous-cell carcinoma; Urology; Larynx; Oncology; Chemotherapy; Internal medicine; Surgery; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001907189,0.001672869,0.002180814,0.0004401877,0.0003596802,0.000717191,0.000991215,0.001418149,0.006067294],"category_scores_gemma":[0.001108329,0.0006501113,0.001564506,0.0004897313,0.001084246,0.0006328027,0.0004927269,0.002509164,0.0009226807],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009239987,"about_ca_system_score_gemma":0.002190077,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001012607,"about_ca_topic_score_gemma":0.002492749,"domain_scores_codex":[0.9994092,0.0003305048,0.00003853565,0.00008643721,0.0000451928,0.00009020835],"domain_scores_gemma":[0.9992587,0.0001623857,0.0001680147,0.00004169098,0.00002863251,0.0003406133],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9525628,0.01476116,0.001653727,0.0004160698,0.0005089683,0.00004984143,0.00008650852,0.0007278147,0.005958129,0.000090025,0.001016037,0.02216901],"study_design_scores_gemma":[0.8204403,0.1744516,0.002484475,0.0000208658,0.000371947,0.00005100655,0.00001938015,0.0004035735,0.0009135034,0.00007755565,0.0007553093,0.00001058256],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918773,0.001556381,0.0003067549,0.0003655417,0.0001370006,0.003924859,0.000692322,0.00006164646,0.001078196],"genre_scores_gemma":[0.980454,0.00236201,0.001797507,0.0009998359,0.0003426333,0.009164499,0.001295902,0.00002045203,0.003563113],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006067294,"threshold_uncertainty_score":0.02029717,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06176604674376193,"score_gpt":0.4350159016102489,"score_spread":0.373249854866487,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}