{"id":"W2143306615","doi":"10.1073/pnas.1506491112","title":"FXR1P is a GSK3β substrate regulating mood and emotion processing","year":2015,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"GSK-3; Mood; Prefrontal cortex; Mood disorders; Bipolar disorder; Mood stabilizer; Schizophrenia (object-oriented programming); Psychology; GSK3B; Phosphorylation; Biology; Neuroscience; Psychiatry; Genetics; Cognition; Anxiety","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003986974,0.00005647262,0.00005522116,0.00003542586,0.00008994088,0.00001852682,0.0001889222,0.00004782271,8.037039e-7],"category_scores_gemma":[0.0001130863,0.00004154444,0.00001990829,0.000183347,0.000271615,0.00001526316,0.00009918987,0.00003890099,1.481749e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004349212,"about_ca_system_score_gemma":0.00003388682,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001326059,"about_ca_topic_score_gemma":6.13174e-8,"domain_scores_codex":[0.9992392,0.000002576961,0.000143493,0.0001717557,0.00036053,0.00008243055],"domain_scores_gemma":[0.9996402,0.000003117481,0.0001662372,0.000004246508,0.0001579095,0.00002829733],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00000871717,0.00001350849,0.01074002,0.00002893859,0.000003959721,5.636712e-10,0.0001951121,0.00003874924,0.9874159,0.000434974,0.0002650573,0.0008550333],"study_design_scores_gemma":[0.0001928123,0.00006383121,0.1733987,0.00003604857,0.000004405033,0.000006907126,0.0003939678,0.0007979923,0.8156534,0.009252209,0.0001307034,0.00006907667],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954717,0.0001973755,0.000001539987,0.0009448004,0.000006841698,0.00006508785,0.000002584552,0.000001950819,0.003308184],"genre_scores_gemma":[0.9983261,0.00002960802,0.001352071,0.0001805753,0.00001422787,0.000002160615,2.054763e-7,0.000002836252,0.00009219475],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1717625,"threshold_uncertainty_score":0.1694133,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04164497104216191,"score_gpt":0.2899511233853201,"score_spread":0.2483061523431582,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}