{"id":"W2143358417","doi":"10.1158/1078-0432.ccr-03-0041","title":"Improved Therapeutic Responses in a Xenograft Model of Human B Lymphoma (Namalwa) for Liposomal Vincristine<b><i>versus</i></b>Liposomal Doxorubicin Targeted via Anti-CD19 IgG2a or Fab′ Fragments","year":2004,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":114,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Animal Health Research Institute","keywords":"Doxorubicin; Liposome; Vincristine; Pharmacology; In vivo; Medicine; Cytotoxicity; Pharmacokinetics; Monoclonal antibody; CD19; Chemistry; Cancer research; In vitro; Antibody; Chemotherapy; Immunology; Cyclophosphamide; Internal medicine; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.003746928,0.0004641658,0.001176283,0.0006253181,0.0005870914,0.00004625844,0.001129724,0.0008823678,0.0004088132],"category_scores_gemma":[0.001259905,0.0003811058,0.0004794059,0.0007681524,0.001712414,0.0002157052,0.0003321398,0.001105465,0.00004546843],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003761076,"about_ca_system_score_gemma":0.001887512,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002279104,"about_ca_topic_score_gemma":0.0008036824,"domain_scores_codex":[0.9936279,0.001860881,0.00175609,0.0009683634,0.0002716795,0.001515064],"domain_scores_gemma":[0.9947588,0.003236218,0.0003698871,0.0009569339,0.0005824903,0.00009570012],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.09622513,0.001801454,0.002404702,0.0001148533,0.0005664102,0.00001289691,0.0005369838,0.0001259457,0.8848631,0.0002315294,0.0001789861,0.01293801],"study_design_scores_gemma":[0.06413309,0.01389707,0.03419767,0.0004786763,0.0001388498,0.00002192288,0.0005695115,0.0007614584,0.8789836,0.001226991,0.004690519,0.0009006196],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9879333,0.007647695,0.0005726304,0.000889987,0.0008473538,0.001719838,0.0002521575,0.00008250409,0.00005454443],"genre_scores_gemma":[0.9948465,0.001326882,0.0002773022,0.0002843492,0.0001189651,0.0005735964,0.00009081822,0.0001022797,0.002379344],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03209204,"threshold_uncertainty_score":0.9998641,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1742405940135476,"score_gpt":0.4634790582557968,"score_spread":0.2892384642422493,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}