{"id":"W2143358417","doi":"10.1158/1078-0432.ccr-03-0041","title":"Improved Therapeutic Responses in a Xenograft Model of Human B Lymphoma (Namalwa) for Liposomal Vincristine<b><i>versus</i></b>Liposomal Doxorubicin Targeted via Anti-CD19 IgG2a or Fab′ Fragments","year":2004,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":114,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Animal Health Research Institute","keywords":"Doxorubicin; Liposome; Vincristine; Pharmacology; In vivo; Medicine; Cytotoxicity; Pharmacokinetics; Monoclonal antibody; CD19; Chemistry; Cancer research; In vitro; Antibody; Chemotherapy; Immunology; Cyclophosphamide; Internal medicine; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001416987,0.0004183689,0.0002773059,0.0001703699,0.00009603141,0.0002181187,0.0001782817,0.0002730521,0.001259799],"category_scores_gemma":[0.00009103188,0.0001157576,0.0001558795,0.000107534,0.0001676487,0.0002477948,0.00009082093,0.0005167323,0.0002771053],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002770014,"about_ca_system_score_gemma":0.000154337,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001115945,"about_ca_topic_score_gemma":0.0009329688,"domain_scores_codex":[0.9999267,0.00001316659,0.000005392566,0.00002034353,0.00001937352,0.00001495269],"domain_scores_gemma":[0.999911,0.0000174236,0.0000286394,0.00001132105,0.0000108466,0.00002081106],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004999976,0.0001654735,0.0001764766,0.00002819279,0.000006653236,0.00002304288,0.00001653294,0.00008236466,0.9976902,0.00003573538,0.00003990731,0.001235455],"study_design_scores_gemma":[0.00008333227,0.002767347,0.002115052,0.000003902181,0.00002930811,0.0001550676,0.00001882418,0.001103427,0.9927128,0.0000104726,0.0009970462,0.000003399099],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970413,0.0006601217,0.001067898,0.00005063226,0.00002013539,0.00003940086,0.0001734725,0.00007998731,0.0008671527],"genre_scores_gemma":[0.9957476,0.0003921643,0.001480516,0.00003122549,0.000005792729,0.00006740899,0.0003162735,0.0000243876,0.001934604],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001259799,"threshold_uncertainty_score":0.004214466,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1742405940135476,"score_gpt":0.4634790582557968,"score_spread":0.2892384642422493,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}