{"id":"W2143395547","doi":"10.4049/jimmunol.1203057","title":"Regulation of Th1 Cells and Experimental Autoimmune Encephalomyelitis by Glycogen Synthase Kinase-3","year":2013,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Mental Health; Canadian Institutes of Health Research","keywords":"Experimental autoimmune encephalomyelitis; GSK-3; Multiple sclerosis; Myelin; T cell; Immunology; Myelin oligodendrocyte glycoprotein; Encephalomyelitis; GSK3B; Biology; Oligodendrocyte; Myelin basic protein; Glycogen synthase; Kinase; Central nervous system; Endocrinology; Cell biology; Glycogen; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003733709,0.0007268175,0.0003153257,0.0003850657,0.0001933287,0.000275486,0.0002500182,0.0004240018,0.001378487],"category_scores_gemma":[0.0001318055,0.0001652674,0.0005032209,0.0001948837,0.0004715329,0.0002470065,0.0002210607,0.001138285,0.0003502871],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003554068,"about_ca_system_score_gemma":0.0003620923,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004498994,"about_ca_topic_score_gemma":0.001133439,"domain_scores_codex":[0.9997063,0.00008480383,0.00003412538,0.0000400449,0.00005610176,0.00007858915],"domain_scores_gemma":[0.9998888,0.00001196415,0.00004211264,0.00001328183,0.00001077461,0.00003315717],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001067783,0.0002148247,0.0004925992,0.0002189619,0.00001417685,0.0001299069,0.00003297222,0.0001269674,0.9946055,0.0002231837,0.0001438238,0.002729169],"study_design_scores_gemma":[0.0006463369,0.003910358,0.01934032,0.00007411317,0.00006332003,0.0005152553,0.00009277338,0.001206832,0.9678986,0.0003747951,0.005856518,0.00002060783],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9824504,0.009636023,0.002550907,0.000422084,0.0001926228,0.000203832,0.0008114837,0.0001769198,0.003555611],"genre_scores_gemma":[0.9898927,0.003939522,0.002593816,0.0001798055,0.00004825289,0.0002921127,0.0004644936,0.00002258149,0.00256668],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001378487,"threshold_uncertainty_score":0.004611492,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005072827096571353,"score_gpt":0.2118972513409766,"score_spread":0.2068244242444052,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}