{"id":"W2143410485","doi":"10.1128/mcb.01034-10","title":"HEB-Deficient T-Cell Precursors Lose T-Cell Potential and Adopt an Alternative Pathway of Differentiation","year":2010,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Biology; Cell biology; Cell fate determination; T cell; Cellular differentiation; GATA3; Transcription factor; Immunology; Genetics; Gene; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007567262,0.0003058314,0.0002000934,0.0002035185,0.0001465543,0.0003811173,0.0002408256,0.0002659216,0.001590905],"category_scores_gemma":[0.00007685145,0.0001525548,0.0001205176,0.0001075174,0.0002146656,0.0002458425,0.0003761859,0.0006899448,0.0008036593],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001919231,"about_ca_system_score_gemma":0.0001435236,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003814888,"about_ca_topic_score_gemma":0.0006080418,"domain_scores_codex":[0.9998759,0.0000140041,0.00000977438,0.00002776475,0.00004030742,0.00003219398],"domain_scores_gemma":[0.9998719,0.00001281714,0.00003166319,0.00001280734,0.00001296387,0.00005781198],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002537298,0.000006914164,0.0001609177,0.000007013729,0.000001629585,0.00004913555,0.000007076407,0.00001778361,0.9992064,0.00007635395,0.000007399317,0.0004341033],"study_design_scores_gemma":[0.00001388828,0.00008410103,0.006049137,0.00000448012,0.000006762205,0.0007729382,0.0000388305,0.0006815027,0.990025,0.00007849043,0.002240227,0.000004544981],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945521,0.0009815529,0.002809878,0.00002647399,0.00001225423,0.00001212938,0.0001381491,0.00006059817,0.00140694],"genre_scores_gemma":[0.9914237,0.000560815,0.001635151,0.00004328433,0.00000508976,0.00001804848,0.0003207158,0.00002980006,0.005963426],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001590905,"threshold_uncertainty_score":0.005322099,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004040390612563761,"score_gpt":0.1957952092171735,"score_spread":0.1917548186046097,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}