{"id":"W2143417586","doi":"10.1007/s11010-011-0776-7","title":"Regulation of Rac1 and Cdc42 activation in thrombin- and collagen-stimulated CHRF-288-11 cells","year":2011,"lang":"en","type":"article","venue":"Molecular and Cellular Biochemistry","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"Child Health Research Foundation; University of Manitoba; Heart and Stroke Foundation of Canada","keywords":"RAC1; Thrombin; CDC42; Cell biology; Calmodulin; Chemistry; Biochemistry; Biology; Immunology; GTPase; Platelet; Signal transduction; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001822192,0.0001852808,0.0001826307,0.0000580186,0.00004976242,0.00001627357,0.0000609434,0.0002559748,0.00001953331],"category_scores_gemma":[0.00003241381,0.0002015326,0.00004037445,0.0001153743,0.000148753,0.000007789052,0.00009349726,0.00005508195,3.271954e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001048186,"about_ca_system_score_gemma":0.00003555463,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004288482,"about_ca_topic_score_gemma":0.000002667273,"domain_scores_codex":[0.9989884,0.00005108648,0.0002579857,0.0003968994,0.000115026,0.0001905508],"domain_scores_gemma":[0.9994753,0.000006386772,0.0001246682,0.0002294783,0.00006214406,0.0001020026],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007636257,0.00005094938,0.00100924,0.0001162083,0.00002199995,0.000005277703,0.00006532446,0.00001327823,0.9980869,0.0001276606,0.00001411637,0.0004127054],"study_design_scores_gemma":[0.0008560915,0.00007449256,0.00181998,0.00006269126,0.00002343601,0.00001081984,0.00007636273,0.0002826883,0.996207,0.000298857,0.00007126044,0.0002163376],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946839,0.001515579,0.003168546,0.00002950799,0.00001687984,0.000211726,0.000006340556,0.000009175257,0.0003583512],"genre_scores_gemma":[0.9987593,0.00004289088,0.0008896561,0.00005261681,0.0000201038,0.000009488533,0.0001157314,0.00002100373,0.00008920786],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004075407,"threshold_uncertainty_score":0.8218262,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008108329039885271,"score_gpt":0.2008046859460415,"score_spread":0.1926963569061562,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}