{"id":"W2143424558","doi":"10.4049/jimmunol.1101118","title":"Adjuvant Immunotherapy of Experimental Autoimmune Encephalomyelitis: Immature Myeloid Cells Expressing CXCL10 and CXCL16 Attract CXCR3+CXCR6+ and Myelin-Specific T Cells to the Draining Lymph Nodes Rather Than the Central Nervous System","year":2012,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital","funders":"National Institute of Neurological Disorders and Stroke; National Cancer Institute","keywords":"CXCR3; Medicine; Immunotherapy; Lymph; Immunology; Adjuvant; Myelin; Experimental autoimmune encephalomyelitis; Central nervous system; Cancer research; Immune system; Pathology; Chemokine; Internal medicine; Chemokine receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002138156,0.0005989893,0.0003573287,0.0002004379,0.0000798229,0.0002509189,0.0001299534,0.0002853693,0.0007927453],"category_scores_gemma":[0.00009139154,0.00009179278,0.0002173678,0.0001154906,0.0001874623,0.000218514,0.0001522954,0.0008204753,0.0003068191],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001429717,"about_ca_system_score_gemma":0.0002232618,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001661303,"about_ca_topic_score_gemma":0.0003593471,"domain_scores_codex":[0.9998257,0.00004102015,0.0000171872,0.00002814927,0.00002488572,0.0000631436],"domain_scores_gemma":[0.9999123,0.000009341406,0.0000317386,0.000008935564,0.000008115961,0.00002967167],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001465621,0.00007529432,0.0001331015,0.00005287825,0.000002239062,0.00002492138,0.000008283438,0.0000249216,0.9978399,0.00002589991,0.0000189021,0.001647047],"study_design_scores_gemma":[0.0001310638,0.003390049,0.006244523,0.00002239101,0.00003331704,0.0006348763,0.00002419082,0.0005407207,0.9860311,0.00005151581,0.002891072,0.000005271698],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953135,0.002503446,0.001250716,0.00008174819,0.00004260751,0.00005296681,0.0001137333,0.00006679707,0.0005743375],"genre_scores_gemma":[0.9926937,0.001928411,0.003147658,0.00008830857,0.00005873353,0.00007227545,0.0002417562,0.00001534721,0.001753941],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007927453,"threshold_uncertainty_score":0.002651989,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01142452918299806,"score_gpt":0.2284808709181079,"score_spread":0.2170563417351098,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}