{"id":"W2143481129","doi":"10.1073/pnas.0308065101","title":"The Shc adaptor protein is critical for VEGF induction by Met/HGF and ErbB2 receptors and for early onset of tumor angiogenesis","year":2004,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Liver physiology and pathology","field":"Medicine","cited_by":72,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"","keywords":"Receptor tyrosine kinase; Angiogenesis; GRB2; Signal transducing adaptor protein; Neuropilin 1; Cancer research; Vascular endothelial growth factor; Cell biology; Hepatocyte growth factor; Biology; Vascular endothelial growth factor A; Receptor; Signal transduction; Chemistry; VEGF receptors; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007958792,0.00005838219,0.0001375786,0.00005553319,0.0002138985,0.000005741227,0.000134432,0.00007348985,0.000001364593],"category_scores_gemma":[0.0008996474,0.00003321404,0.0000462758,0.0001595094,0.001481515,0.0001446708,0.00003432234,0.00006575335,6.400254e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001143218,"about_ca_system_score_gemma":0.00003656933,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005145387,"about_ca_topic_score_gemma":3.544899e-8,"domain_scores_codex":[0.9993091,0.000005294718,0.0001803738,0.0001629024,0.0002387841,0.0001035089],"domain_scores_gemma":[0.9993228,0.0002385679,0.0001515695,0.000006495181,0.0002530776,0.00002743488],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003353157,0.00006074375,0.005981092,0.0002067509,0.00003471319,3.418648e-9,0.0004494505,3.608768e-7,0.9474332,0.04413664,0.0009537606,0.0004079513],"study_design_scores_gemma":[0.000501483,0.0007365884,0.05372962,0.0000935748,0.00005052318,0.00001773259,0.0003504074,0.00002230195,0.8469577,0.09730835,0.0001845803,0.00004715631],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989517,0.0003158897,0.000003134199,0.009569155,0.00001638669,0.0004698281,0.00005936914,0.000003221973,0.00004596256],"genre_scores_gemma":[0.9957036,0.00001887587,0.003869783,0.0002383856,0.00005236677,0.0000586514,2.740275e-7,0.000002738873,0.00005533127],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1004755,"threshold_uncertainty_score":0.5458702,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05000385001772215,"score_gpt":0.3331895562729205,"score_spread":0.2831857062551983,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}