{"id":"W2143481129","doi":"10.1073/pnas.0308065101","title":"The Shc adaptor protein is critical for VEGF induction by Met/HGF and ErbB2 receptors and for early onset of tumor angiogenesis","year":2004,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Liver physiology and pathology","field":"Medicine","cited_by":72,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"","keywords":"Receptor tyrosine kinase; Angiogenesis; GRB2; Signal transducing adaptor protein; Neuropilin 1; Cancer research; Vascular endothelial growth factor; Cell biology; Hepatocyte growth factor; Biology; Vascular endothelial growth factor A; Receptor; Signal transduction; Chemistry; VEGF receptors; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000111606,0.0002657241,0.000141589,0.0002422975,0.0002947839,0.0002835358,0.0001289773,0.0002805267,0.001330978],"category_scores_gemma":[0.0001388215,0.000116169,0.0002023551,0.0001593924,0.000202636,0.0001473972,0.0002898078,0.0004351678,0.0004183883],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004738062,"about_ca_system_score_gemma":0.0003913187,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001277314,"about_ca_topic_score_gemma":0.001550414,"domain_scores_codex":[0.9998786,0.00001332466,0.00000979049,0.00002374731,0.00003789917,0.00003664395],"domain_scores_gemma":[0.999836,0.00001979132,0.00005355299,0.00001523799,0.00002047783,0.00005492574],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001433906,0.00001606058,0.0008812152,0.00003167909,0.000004096005,0.0001380164,0.000007529979,0.00006014181,0.9969721,0.0001650285,0.00008374874,0.001496909],"study_design_scores_gemma":[0.00003223683,0.0001875035,0.05885075,0.00001263654,0.00002102002,0.001249437,0.00004774278,0.001960973,0.9292637,0.0001407453,0.008220203,0.00001302124],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935109,0.002106324,0.002054792,0.0001020637,0.0000334301,0.00003064304,0.0004606279,0.00007883925,0.001622364],"genre_scores_gemma":[0.995352,0.0004113087,0.001430097,0.0000482218,0.00001261036,0.00003265705,0.000825642,0.00001418473,0.001873162],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001330978,"threshold_uncertainty_score":0.004452527,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05000385001772215,"score_gpt":0.3331895562729205,"score_spread":0.2831857062551983,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}