{"id":"W2143487186","doi":"10.1183/09031936.00104612","title":"Macitentan for the treatment of idiopathic pulmonary fibrosis: the randomised controlled MUSIC trial","year":2013,"lang":"en","type":"article","venue":"European Respiratory Journal","topic":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","field":"Medicine","cited_by":274,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Actelion Pharmaceuticals; Ege Üniversitesi; Johns Hopkins University; National Jewish Health; Drexel University; College of Medicine, Drexel University; University of Alberta; Cleveland Clinic Foundation; Cleveland Clinic; University of California, Davis; Ankara Universitesi; Yale University","keywords":"Medicine; Placebo; Idiopathic pulmonary fibrosis; Internal medicine; Vital capacity; Pulmonary function testing; Endothelin receptor antagonist; Gastroenterology; Lung; Endothelin receptor; Pathology; Lung function; Diffusing capacity; Receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001271936,0.0008103147,0.00187802,0.0003261536,0.0002887856,0.0006093279,0.0006763838,0.001311774,0.007769279],"category_scores_gemma":[0.001974595,0.0002501462,0.001104089,0.0002918455,0.0004979144,0.0005989176,0.0003563058,0.001679625,0.0005894214],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003939742,"about_ca_system_score_gemma":0.0006629785,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007621911,"about_ca_topic_score_gemma":0.001712884,"domain_scores_codex":[0.9994934,0.0003264684,0.00003931471,0.00005367389,0.00003744562,0.00004972903],"domain_scores_gemma":[0.9995277,0.0001445406,0.0001373702,0.00003761348,0.00002776194,0.0001249981],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9672562,0.001918508,0.0005810215,0.001778674,0.001061761,0.00005721732,0.00002928632,0.000220467,0.002187106,0.0002923218,0.001358876,0.02325851],"study_design_scores_gemma":[0.9841385,0.01266211,0.001534354,0.00007257966,0.0003198802,0.00003117616,0.000009790341,0.000185682,0.0001185533,0.0001039494,0.000817149,0.000006171642],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9404647,0.04151068,0.001153435,0.002625384,0.001896471,0.004928972,0.001605379,0.0002313164,0.005583627],"genre_scores_gemma":[0.9711446,0.01048308,0.00216424,0.002365525,0.001107484,0.00664783,0.001605055,0.00002218927,0.004460023],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007769279,"threshold_uncertainty_score":0.02599084,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03224618324784464,"score_gpt":0.2664576518065309,"score_spread":0.2342114685586863,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}