{"id":"W2143526409","doi":"10.1126/science.1125691","title":"Retinoid Signaling Determines Germ Cell Fate in Mice","year":2006,"lang":"en","type":"article","venue":"Science","topic":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1011,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of British Columbia","funders":"","keywords":"Biology; Germ cell; Oogenesis; Spermatogenesis; Retinoic acid; Meiosis; Cell biology; Germ line development; Retinoid; Embryo; Oocyte; Ovary; Gametogenesis; Gonad; Genetics; Endocrinology; Embryogenesis; Cell culture; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006002465,0.0006625917,0.0005383937,0.001723629,0.000712334,0.001082923,0.001055105,0.001375876,0.005954353],"category_scores_gemma":[0.0003394845,0.001209317,0.0005147007,0.0004600074,0.001035724,0.0005825518,0.0007106331,0.002133115,0.004463915],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000789389,"about_ca_system_score_gemma":0.0005652593,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007905703,"about_ca_topic_score_gemma":0.00120561,"domain_scores_codex":[0.9992477,0.0001093543,0.00008091798,0.0002210033,0.0002133279,0.0001277818],"domain_scores_gemma":[0.9993218,0.0001081936,0.0002523359,0.0001026356,0.00004731341,0.0001677777],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003030861,0.00006219928,0.0002974448,0.00005060712,0.000009753267,0.0001529864,0.00005461231,0.00009382294,0.9948456,0.0009632754,0.0001839283,0.002982683],"study_design_scores_gemma":[0.0002905818,0.0004016788,0.005464803,0.00008669077,0.00006295452,0.001270212,0.00007732735,0.001031447,0.963519,0.0009752518,0.02679468,0.00002534138],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9342209,0.006312281,0.02870341,0.001314296,0.0002289135,0.0004945016,0.00786632,0.002674393,0.01818501],"genre_scores_gemma":[0.9207361,0.006054295,0.02422053,0.0006787524,0.00009784009,0.0006662752,0.005612828,0.001460041,0.04047322],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005954353,"threshold_uncertainty_score":0.01991928,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007335133026947075,"score_gpt":0.2442844961769589,"score_spread":0.2369493631500118,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}