{"id":"W2143599673","doi":"10.1016/s0149-2918(03)80339-9","title":"The effects of intramuscular interferon beta-Ia in patients at high risk for development of multiple sclerosis: A post hoc analysis of data from CHAMPS","year":2003,"lang":"en","type":"article","venue":"Clinical Therapeutics","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Michael's Hospital; University of Toronto","funders":"Biogen","keywords":"Medicine; Post-hoc analysis; Multiple sclerosis; Interferon beta-1a; Magnetic resonance imaging; Placebo; Subgroup analysis; Population; Asymptomatic; Internal medicine; Nuclear medicine; Confidence interval; Radiology; Interferon beta; Pathology; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006734194,0.001035382,0.002814834,0.0007443524,0.00080492,0.000731846,0.0007132289,0.001008227,0.002693121],"category_scores_gemma":[0.01113704,0.0003761547,0.002166253,0.0007341852,0.0009663583,0.0009830545,0.0006079528,0.001189837,0.0002786031],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001112999,"about_ca_system_score_gemma":0.001412803,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003590752,"about_ca_topic_score_gemma":0.004787243,"domain_scores_codex":[0.9954721,0.003418086,0.0002476682,0.0003161522,0.0002451703,0.000300897],"domain_scores_gemma":[0.9841378,0.01049998,0.00231433,0.001196072,0.001010985,0.0008407807],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.862002,0.002236395,0.1133284,0.0003587823,0.005750097,0.0002246807,0.0004070669,0.0007766278,0.002971794,0.0001142964,0.0009043827,0.01092558],"study_design_scores_gemma":[0.1117569,0.2232696,0.6435636,0.00009085095,0.01081591,0.0003795785,0.0009200626,0.002655262,0.004318064,0.0002315831,0.001843592,0.0001549637],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990062,0.000317544,0.00006642013,0.00004433713,0.00001783765,0.00008980226,0.0002027829,0.000007373837,0.0002477005],"genre_scores_gemma":[0.9980664,0.0001344421,0.0002995728,0.00007934226,0.00007593336,0.0001981667,0.0006521943,0.000007864597,0.0004862885],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006734194,"threshold_uncertainty_score":0.03561425,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2044316374487832,"score_gpt":0.4114381665685705,"score_spread":0.2070065291197872,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}