{"id":"W2143635309","doi":"10.1002/adsc.200606213","title":"Double Carbonylation Reactions of Enynols and Thiols to Form Thioester Substituted 6‐Membered Ring Lactones","year":2006,"lang":"en","type":"article","venue":"Advanced Synthesis & Catalysis","topic":"Marine Sponges and Natural Products","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"National Key Research and Development Program of China; Program for New Century Excellent Talents in University; National Natural Science Foundation of China","keywords":"Chemistry; Carbonylation; Thioester; Ring (chemistry); Phosphine; Palladium; Lactone; Stereochemistry; Organic chemistry; Medicinal chemistry; Catalysis; Carbon monoxide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001213412,0.0001469591,0.0002187759,0.00009401831,0.00007702522,0.00001576702,0.00009706182,0.00009035595,0.00001193859],"category_scores_gemma":[0.0001235188,0.0001326864,0.00007828503,0.0002057502,0.00002908089,0.0000216563,0.00008050616,0.00005331838,0.000002648906],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001533928,"about_ca_system_score_gemma":0.00001275215,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009752859,"about_ca_topic_score_gemma":0.0008981602,"domain_scores_codex":[0.9990807,0.00001719759,0.0002580541,0.0003557395,0.00010956,0.0001787159],"domain_scores_gemma":[0.9993044,0.00003997437,0.0001225485,0.0003853066,0.00009725086,0.00005050242],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001375581,0.00003270408,0.003577793,0.00003609362,0.0000596032,6.579507e-7,0.00002174107,0.0005849446,0.9866996,0.0001408316,0.00002158804,0.008686827],"study_design_scores_gemma":[0.0002526294,0.0000280685,0.02987466,0.00002403553,0.00008632417,0.000005229925,0.00002810142,0.00002822442,0.9645203,0.0001013706,0.004863113,0.0001879722],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969317,0.0004271856,0.00009799626,0.0001897971,0.00005455782,0.000202637,0.00001331715,0.00001719826,0.00206555],"genre_scores_gemma":[0.9973868,0.0001322165,0.00136192,0.00001894729,0.00009637354,0.00002848891,0.0001470609,0.00001680847,0.00081139],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02629687,"threshold_uncertainty_score":0.5410795,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007004428420591038,"score_gpt":0.2394323442501831,"score_spread":0.2324279158295921,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}