{"id":"W2143734577","doi":"10.1073/pnas.1211002109","title":"Bacteria of the human gut microbiome catabolize red seaweed glycans with carbohydrate-active enzyme updates from extrinsic microbes","year":2012,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Seaweed-derived Bioactive Compounds","field":"Agricultural and Biological Sciences","cited_by":347,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research","keywords":"Glycan; Gut microbiome; Microbiome; Catabolism; Biology; Bacteria; Enzyme; Microbiology; Red algae; Algae; Biochemistry; Chemistry; Bioinformatics; Ecology; Glycoprotein; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004687554,0.000182453,0.0002621135,0.000047147,0.0003876869,0.0000393858,0.001410153,0.0001111864,0.00007200912],"category_scores_gemma":[0.0001086354,0.00005897565,0.0001163411,0.001237999,0.001624564,0.0006182011,0.0003186668,0.0001764728,0.000001134296],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005388938,"about_ca_system_score_gemma":0.00002110116,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007099195,"about_ca_topic_score_gemma":0.0000093525,"domain_scores_codex":[0.9982993,0.00002791919,0.0003447425,0.0003079559,0.0007263053,0.000293772],"domain_scores_gemma":[0.9986543,0.0001747322,0.000720231,0.00001407763,0.0003771002,0.00005953051],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003688913,0.00008665262,0.02276701,0.000008729649,0.00003428595,2.485118e-9,0.0002765195,0.00000136785,0.9753712,0.001010794,0.000190189,0.0002163876],"study_design_scores_gemma":[0.00008776139,0.00003584472,0.4362861,0.00004501734,0.00001653631,0.000002079562,0.0004137828,0.000003498276,0.5616156,0.0008936779,0.0005202647,0.00007983134],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955996,0.0001479881,3.469501e-8,0.002516204,0.00004672819,0.0002622232,0.0002633684,0.00001380707,0.001150062],"genre_scores_gemma":[0.9992796,0.000009618812,0.0002671078,0.0001496283,0.0001788974,0.0000101141,0.000004071888,0.000001702889,0.00009923064],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4137555,"threshold_uncertainty_score":0.5985774,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03689448669658123,"score_gpt":0.2558261642729552,"score_spread":0.2189316775763739,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}