{"id":"W2143747033","doi":"10.1093/toxsci/kft115","title":"Deprenyl Enhances the Teratogenicity of Hydroxyurea in Organogenesis Stage Mouse Embryos","year":2013,"lang":"en","type":"article","venue":"Toxicological Sciences","topic":"Neurogenetic and Muscular Disorders Research","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Oxidative stress; Teratology; Glyceraldehyde 3-phosphate dehydrogenase; Endocrinology; Hydroxycarbamide; Internal medicine; Biology; Glutathione; Chromosomal translocation; Embryo; Pharmacology; Gestation; Dehydrogenase; Pregnancy; Medicine; Biochemistry; Chemotherapy; Cell biology; Enzyme; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004907052,0.00009495221,0.0002089929,0.00006779783,0.0001184385,0.00003152163,0.0003601253,0.00006815841,0.00195281],"category_scores_gemma":[0.0002952185,0.00004613907,0.0000710519,0.0006003406,0.0008732341,0.0000629666,0.000121639,0.0001286078,0.00005089152],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001531961,"about_ca_system_score_gemma":0.0001095248,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001718446,"about_ca_topic_score_gemma":0.0001050531,"domain_scores_codex":[0.998565,0.0001397289,0.0002257397,0.0002786168,0.0004622241,0.0003287339],"domain_scores_gemma":[0.9994398,0.0001743224,0.00005032155,0.0001861314,0.00004977368,0.0000996081],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001973916,0.0003297345,0.1182823,0.0000191237,0.000010705,0.000007584386,0.0001432444,0.0000386973,0.8755696,0.0001820858,0.0001595817,0.005237697],"study_design_scores_gemma":[0.0004460384,0.0008034558,0.2923589,0.00001149507,0.000009946427,0.000007010603,0.0007234412,0.0005278424,0.7042364,0.0002889713,0.0004866499,0.00009989212],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942905,0.0003700579,0.00003630091,0.001520858,0.00002132746,0.0006321874,0.000001815813,0.00001728837,0.003109628],"genre_scores_gemma":[0.9981268,0.0001712222,0.0002427621,0.0006017958,0.00001520079,0.0000683151,5.867124e-7,0.000003517497,0.0007698216],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1740766,"threshold_uncertainty_score":0.9989595,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0414830133669841,"score_gpt":0.3207719519390891,"score_spread":0.279288938572105,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}