{"id":"W2143748029","doi":"10.1002/bit.20474","title":"Medium optimization for hen egg white lysozyme production by recombinant <i>Aspergillus niger</i> using statistical methods","year":2005,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"Enzyme Production and Characterization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"","keywords":"Aspergillus niger; Lysozyme; Recombinant DNA; Chemistry; Egg white; Food science; Biochemistry; Chromatography","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005921386,0.0009868329,0.00150299,0.001094587,0.0004855967,0.001122562,0.0006283515,0.0004097313,0.001124465],"category_scores_gemma":[0.006819959,0.0003688586,0.001153346,0.001380004,0.0006041609,0.0004480518,0.0006212868,0.000812799,0.0002344792],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007985599,"about_ca_system_score_gemma":0.001683887,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007485517,"about_ca_topic_score_gemma":0.001067648,"domain_scores_codex":[0.9944634,0.002486552,0.0007432025,0.000632917,0.001373825,0.0003000537],"domain_scores_gemma":[0.9958818,0.00251244,0.000690138,0.0002905014,0.0005603635,0.00006477785],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002549096,0.0007537703,0.005217639,0.001197715,0.0002534646,0.0001522336,0.0002771861,0.02413847,0.8937109,0.001632139,0.0004641529,0.06965329],"study_design_scores_gemma":[0.0001389783,0.006669067,0.01467742,0.00003696391,0.0002197756,0.000130424,0.0001995846,0.05442623,0.9179857,0.0009415648,0.004481104,0.00009319064],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5910637,0.0007098285,0.4018416,0.0001366144,0.00007696509,0.001921923,0.001383265,0.001384572,0.00148167],"genre_scores_gemma":[0.5800997,0.0006296264,0.4121031,0.00006872153,0.00001706124,0.00477492,0.001175704,0.0002870793,0.0008440524],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005921386,"threshold_uncertainty_score":0.03131562,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01028505295304441,"score_gpt":0.2710246756819868,"score_spread":0.2607396227289424,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}