{"id":"W2143748029","doi":"10.1002/bit.20474","title":"Medium optimization for hen egg white lysozyme production by recombinant <i>Aspergillus niger</i> using statistical methods","year":2005,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"Enzyme Production and Characterization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"","keywords":"Aspergillus niger; Lysozyme; Recombinant DNA; Chemistry; Egg white; Food science; Biochemistry; Chromatography","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002174692,0.0001451429,0.0001311703,0.00008101518,0.00009209711,0.00001675423,0.00006907088,0.0003406444,0.00001065358],"category_scores_gemma":[0.0001134929,0.000144442,0.00002549842,0.0001108827,0.00007592416,0.00001334416,0.0000465933,0.00009372333,6.710766e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002168744,"about_ca_system_score_gemma":0.00001638588,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001230012,"about_ca_topic_score_gemma":0.000001209238,"domain_scores_codex":[0.9991457,0.00002643719,0.0001971834,0.0003832089,0.00004402686,0.000203376],"domain_scores_gemma":[0.9996619,0.000005731518,0.00006197978,0.0001740836,0.00005281116,0.00004353949],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003354722,0.00003133636,0.00007133597,0.00002835009,0.00003034925,1.454695e-7,0.00001739052,0.004718329,0.9845386,0.0001194996,0.0005769347,0.009834233],"study_design_scores_gemma":[0.000268264,0.0001277994,0.00004508319,0.00001044557,0.00002866105,0.00004601567,0.00003507708,0.04000244,0.9040175,0.00001165072,0.0552035,0.0002035653],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.1255714,0.0008127762,0.86943,0.00330162,0.0005371353,0.0002311258,0.00002257603,0.00008884604,0.000004560686],"genre_scores_gemma":[0.4949937,0.001165171,0.5020571,0.0001464473,0.000549736,0.00004749032,0.0005774367,0.00004847716,0.0004143842],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.3694224,"threshold_uncertainty_score":0.5890175,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01028505295304441,"score_gpt":0.2710246756819868,"score_spread":0.2607396227289424,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}