{"id":"W2143814503","doi":"10.1073/pnas.0409872102","title":"Characterization of CD56 <sup>–</sup> /CD16 <sup>+</sup> natural killer (NK) cells: A highly dysfunctional NK subset expanded in HIV-infected viremic individuals","year":2005,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":537,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Biology; Natural killer cell; Interleukin 21; CD16; Immunology; Lymphokine-activated killer cell; Immune system; Cytotoxic T cell; Innate immune system; Population; NK-92; Interleukin 12; Cytolysis; Virology; T cell; In vitro; CD8; Medicine; CD3; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001000462,0.0001602999,0.0001387145,0.0002753881,0.0001332045,0.0002585587,0.0001003712,0.0001606216,0.0008953213],"category_scores_gemma":[0.0002209617,0.0000712408,0.00008460748,0.0001294098,0.0001119154,0.000145329,0.0001662566,0.0001533646,0.0003194733],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006477071,"about_ca_system_score_gemma":0.00005638468,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002046175,"about_ca_topic_score_gemma":0.0001760648,"domain_scores_codex":[0.9999335,0.00001008529,0.0000125059,0.00001595357,0.00001411703,0.00001386583],"domain_scores_gemma":[0.99993,0.00001005479,0.00001780487,0.00001151603,0.00001078729,0.00001988974],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004886719,0.00003634149,0.03687675,0.00005228875,0.0000119351,0.0006524862,0.0001452083,0.00008737857,0.9528337,0.0000972855,0.00005843672,0.008659558],"study_design_scores_gemma":[0.00006037756,0.001396257,0.4963295,0.0000353069,0.00009529954,0.02865356,0.0005475081,0.001886786,0.4635558,0.000270979,0.007147998,0.00002071544],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.999049,0.000212802,0.000342198,0.00001076128,0.000001802036,0.000007428206,0.00009074868,0.000004109316,0.0002812144],"genre_scores_gemma":[0.9983297,0.0001716098,0.0007094995,0.00002126499,0.000006487942,0.00001194262,0.0003065339,0.000004866813,0.0004381147],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008953213,"threshold_uncertainty_score":0.002995133,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01658197124290649,"score_gpt":0.2494669644537565,"score_spread":0.23288499321085,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}