{"id":"W2143852804","doi":"10.1038/nrclinonc.2011.21","title":"Antiangiogenic therapy: impact on invasion, disease progression, and metastasis","year":2011,"lang":"en","type":"review","venue":"Nature Reviews Clinical Oncology","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":676,"is_retracted":false,"has_abstract":false,"ca_institutions":"Sunnybrook Health Science Centre","funders":"National Cancer Institute","keywords":"Medicine; Antiangiogenic therapy; Oncology; Disease; Clinical trial; Internal medicine; Adjuvant therapy; Adjuvant; Drug; Angiogenesis; Cancer; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.002355681,0.0008546765,0.003808128,0.0001194624,0.0001069214,0.00002293861,0.0006227661,0.002886958,0.0002077971],"category_scores_gemma":[0.001072026,0.0004612154,0.003752332,0.0002626405,0.0003051129,0.00000502993,0.0003112677,0.001203148,0.0001216508],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006270751,"about_ca_system_score_gemma":0.001163104,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002650415,"about_ca_topic_score_gemma":0.000004632852,"domain_scores_codex":[0.9940569,0.002140475,0.001779742,0.001370348,0.0001736551,0.0004788679],"domain_scores_gemma":[0.9963663,0.0003100659,0.001382285,0.001186918,0.0001310863,0.0006233994],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000222665,0.00037061,0.0001622962,0.001295541,0.0006596995,0.00002041769,0.000001828705,1.723221e-8,0.000001486364,0.00005301352,0.0430285,0.9541839],"study_design_scores_gemma":[0.0004515094,0.002008942,0.0002550919,0.00306282,0.001359267,0.00003701872,5.474778e-7,1.204339e-7,0.000003427978,0.00002624358,0.9922855,0.0005094662],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006510461,0.9964924,0.000007924819,0.00008932428,0.0007864613,0.001915689,0.0001362763,0.00001670822,0.0004900631],"genre_scores_gemma":[0.00006259931,0.9944017,0.0004683106,0.002058339,0.001728004,0.0003913315,0.0005419339,0.0001083674,0.0002394276],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9536744,"threshold_uncertainty_score":0.9997839,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1618734022804451,"score_gpt":0.5144781344395424,"score_spread":0.3526047321590973,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}