{"id":"W2143864965","doi":"10.1128/jvi.02171-12","title":"Intersubtype Differences in the Effect of a Rare p24 Gag Mutation on HIV-1 Replicative Fitness","year":2012,"lang":"en","type":"article","venue":"Journal of Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"AIDS Vancouver; Simon Fraser University","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; U.S. Public Health Service; Wellcome Trust","keywords":"Biology; Mutation; Mutant; Allele; Virology; Genetics; Viral replication; In vitro; Virus; Group-specific antigen; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000396894,0.0002635899,0.0002509247,0.0003026451,0.0001614126,0.0004060978,0.0002312525,0.0003473589,0.00193259],"category_scores_gemma":[0.0006844054,0.0001237587,0.0003201099,0.0001736342,0.0001948659,0.0001440159,0.0002651064,0.0004408525,0.0003963577],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001546259,"about_ca_system_score_gemma":0.0001393827,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003195367,"about_ca_topic_score_gemma":0.0003651804,"domain_scores_codex":[0.9995463,0.0001255046,0.00006171312,0.00008572759,0.0001189285,0.0000617816],"domain_scores_gemma":[0.9995566,0.0001738066,0.00008036549,0.00007215922,0.00003241317,0.00008464336],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002582799,0.00008907105,0.005793132,0.00003027058,0.00004342011,0.0001789679,0.000026141,0.0003409896,0.9873062,0.0001649344,0.00003323527,0.005735315],"study_design_scores_gemma":[0.00003295057,0.002064616,0.1199462,0.00001361561,0.0001205352,0.002802908,0.0000943018,0.003184838,0.8699695,0.0002809919,0.001468426,0.00002118963],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979216,0.0005010741,0.0005523529,0.00001625691,0.000006955206,0.000009470959,0.00008035955,0.00001629545,0.0008956023],"genre_scores_gemma":[0.9992471,0.0001101198,0.0002935757,0.00001633897,0.000003571812,0.00000680419,0.0000910019,0.00000961052,0.0002219553],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00193259,"threshold_uncertainty_score":0.006465137,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01856238321048941,"score_gpt":0.2984849754534981,"score_spread":0.2799225922430086,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}