{"id":"W2143940059","doi":"10.1186/bcr801","title":"The Breast Cancer Family Registry: an infrastructure for cooperative multinational, interdisciplinary and translational studies of the genetic epidemiology of breast cancer","year":2004,"lang":"en","type":"article","venue":"Breast Cancer Research","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":306,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Ontario Institute for Cancer Research; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"National Institute of Environmental Health Sciences; National Cancer Institute; National Institutes of Health; University of California, Irvine; University of Melbourne; Canadian Breast Cancer Research Alliance; National Center for Research Resources; Huntsman Cancer Foundation; Cancer Care Ontario","keywords":"Breast cancer; Medicine; Epidemiology; Family history; Family medicine; Cancer; Genetic epidemiology; Population; Epidemiology of cancer; Oncology; Internal medicine; Environmental health","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007816307,0.0002131108,0.0003063408,0.00007091658,0.0005915202,0.00001482664,0.0005335753,0.0001672563,0.00002608313],"category_scores_gemma":[0.0001033508,0.0001366354,0.0001075118,0.0003280899,0.001985062,0.00001827455,0.0003076595,0.0002681273,1.902509e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002578839,"about_ca_system_score_gemma":0.002109718,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001018321,"about_ca_topic_score_gemma":0.003529848,"domain_scores_codex":[0.997848,0.0003646195,0.0004747616,0.0005320723,0.0003652632,0.0004152677],"domain_scores_gemma":[0.9969937,0.0002536557,0.0002407344,0.0004618018,0.00196496,0.0000851021],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00611501,0.0003959759,0.3425609,0.0008533579,0.002616051,0.000002028936,0.006215153,0.161789,0.2995751,0.003827553,0.01578858,0.1602613],"study_design_scores_gemma":[0.001452136,0.0001184769,0.9860212,0.0002140294,0.00005223261,0.0001230495,0.002032041,0.0003706517,0.004971613,0.003753065,0.0007019905,0.0001895388],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9444414,0.02070897,0.0003828393,0.02514455,0.0003402071,0.0009497422,0.007991901,0.000005887429,0.0000344697],"genre_scores_gemma":[0.9935947,0.003923795,0.0005570948,0.0001722732,0.000525238,0.001019755,0.0000448156,0.00003450416,0.0001278399],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6434602,"threshold_uncertainty_score":0.7314045,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06305866834243463,"score_gpt":0.4426976325341854,"score_spread":0.3796389641917507,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}