{"id":"W2143953700","doi":"10.1093/brain/awq118","title":"The natural history of multiple sclerosis, a geographically based study 10: relapses and long-term disability","year":2010,"lang":"en","type":"article","venue":"Brain","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":718,"is_retracted":false,"has_abstract":true,"ca_institutions":"London Health Sciences Centre; Western University","funders":"Porticus Foundation; Fondazione Italiana Sclerosi Multipla","keywords":"Multiple sclerosis; Natural history; Expanded Disability Status Scale; Medicine; Cohort; Confidence interval; Natural history study; Pediatrics; Disease; Physical therapy; Internal medicine; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001146334,0.0001689779,0.0003243606,0.00006207983,0.0001745366,0.00001871742,0.0001945488,0.00007178921,0.0001026681],"category_scores_gemma":[0.006979814,0.0001051841,0.0001247188,0.0001476395,0.001442287,0.00005663632,0.0001806859,0.0005139639,0.000003689738],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009144925,"about_ca_system_score_gemma":0.0001239517,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001933337,"about_ca_topic_score_gemma":0.004775948,"domain_scores_codex":[0.9982591,0.0002019693,0.0003298171,0.0003590451,0.0005355728,0.0003145378],"domain_scores_gemma":[0.9965951,0.002281212,0.00009141278,0.000677242,0.0001971279,0.0001579242],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004917129,0.0007937672,0.9210474,0.0000836572,0.00008815806,0.000003480467,0.0003410904,1.075962e-7,0.06064332,0.000009082682,0.002535655,0.01396257],"study_design_scores_gemma":[0.002946726,0.0003801187,0.9938923,0.00005581535,0.00003353307,0.00000140653,0.0001440015,0.0002212598,0.0002044068,0.000004006438,0.002015817,0.000100583],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943223,0.001072369,0.000003537601,0.003042698,0.0002512608,0.001126639,0.0000113328,0.00004961025,0.0001202277],"genre_scores_gemma":[0.9986644,0.00005231175,0.0001902618,0.0001415116,0.00007953517,0.0001079181,0.000007667551,0.00001808066,0.0007382732],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07284493,"threshold_uncertainty_score":0.8355994,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04227848539635986,"score_gpt":0.2990271467042017,"score_spread":0.2567486613078418,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}