{"id":"W2143953700","doi":"10.1093/brain/awq118","title":"The natural history of multiple sclerosis, a geographically based study 10: relapses and long-term disability","year":2010,"lang":"en","type":"article","venue":"Brain","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":718,"is_retracted":false,"has_abstract":true,"ca_institutions":"London Health Sciences Centre; Western University","funders":"Porticus Foundation; Fondazione Italiana Sclerosi Multipla","keywords":"Multiple sclerosis; Natural history; Expanded Disability Status Scale; Medicine; Cohort; Confidence interval; Natural history study; Pediatrics; Disease; Physical therapy; Internal medicine; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006950668,0.0003308604,0.0003640387,0.0008642191,0.000712263,0.0007541103,0.0007499819,0.0005435399,0.001220054],"category_scores_gemma":[0.003031378,0.000265025,0.0005387623,0.001144887,0.0005682643,0.0006556188,0.000874693,0.0006793494,0.0004053552],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009225259,"about_ca_system_score_gemma":0.0007350337,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.07834433,"about_ca_topic_score_gemma":0.08225267,"domain_scores_codex":[0.9994329,0.0001790566,0.00004970753,0.0001170398,0.0001039464,0.0001174946],"domain_scores_gemma":[0.9978393,0.0002645588,0.0008733801,0.0002060612,0.0001956355,0.0006211423],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001949135,0.00002734011,0.9986303,0.00001305488,0.00007121312,0.00009848331,0.0002916615,0.00002460447,0.0001036705,0.00001735432,0.00007008613,0.0004573782],"study_design_scores_gemma":[0.000006995184,0.00008946726,0.9991986,0.000005900426,0.00001839967,0.0001606447,0.0003015779,0.00007648972,0.00001102795,0.00001367255,0.0001141879,0.000002932824],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986633,0.0004261336,0.00003778137,0.00004833758,0.000002755296,0.00001148809,0.0004527229,0.000003364376,0.0003542198],"genre_scores_gemma":[0.9991896,0.0001089289,0.00002625382,0.00001417985,0.000006556566,0.00001098328,0.0004526618,0.000003023114,0.0001878475],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07834433,"threshold_uncertainty_score":0.1557767,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04227848539635986,"score_gpt":0.2990271467042017,"score_spread":0.2567486613078418,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}