{"id":"W2143959162","doi":"10.1111/j.1440-1681.2010.05373.x","title":"Attenuation of store‐operated Ca<sup>2+</sup> entry and enhanced expression of TRPC channels in caudal artery smooth muscle from Type 2 diabetic Goto‐Kakizaki rats","year":2010,"lang":"en","type":"article","venue":"Clinical and Experimental Pharmacology and Physiology","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"TRPC; TRPC3; Endocrinology; Internal medicine; Cyclopiazonic acid; TRPC5; Transient receptor potential channel; TRPC1; TRPC6; Stretch-activated ion channel; Chemistry; Voltage-dependent calcium channel; Contraction (grammar); Extracellular; Vascular smooth muscle; Receptor; Biology; T-type calcium channel; Calcium; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001681412,0.0007767869,0.0005546303,0.0005599631,0.0002711756,0.0002816541,0.0002600597,0.0005788402,0.001588309],"category_scores_gemma":[0.0001930126,0.0003749986,0.0005992576,0.0002600984,0.0004869096,0.0003399314,0.0002995027,0.001166422,0.0002519601],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001912038,"about_ca_system_score_gemma":0.0002011879,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00101823,"about_ca_topic_score_gemma":0.001124401,"domain_scores_codex":[0.9998739,0.00001226295,0.00001609465,0.00002757702,0.00003229927,0.00003782363],"domain_scores_gemma":[0.9997081,0.0000183125,0.0001206416,0.00003186622,0.00002563992,0.00009542127],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005874229,0.00006040884,0.000540258,0.0000354137,0.000009732632,0.0001815104,0.00002948947,0.0000140171,0.9978542,0.00003444074,0.00001665801,0.0006364644],"study_design_scores_gemma":[0.0003962726,0.004047263,0.1979425,0.00002987843,0.0002796056,0.002256463,0.0005425154,0.001577281,0.7905805,0.0002288017,0.002072283,0.00004666105],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987229,0.0002937028,0.0006054969,0.00005174466,0.00001846285,0.00001023098,0.0001084245,0.00002850665,0.0001606497],"genre_scores_gemma":[0.9953436,0.0009735738,0.001468254,0.00007414095,0.00003597734,0.00007292888,0.000460925,0.00002260637,0.001548014],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001588309,"threshold_uncertainty_score":0.005313456,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02999969713699554,"score_gpt":0.3447100053064482,"score_spread":0.3147103081694527,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}