{"id":"W2143959162","doi":"10.1111/j.1440-1681.2010.05373.x","title":"Attenuation of store‐operated Ca<sup>2+</sup> entry and enhanced expression of TRPC channels in caudal artery smooth muscle from Type 2 diabetic Goto‐Kakizaki rats","year":2010,"lang":"en","type":"article","venue":"Clinical and Experimental Pharmacology and Physiology","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"TRPC; TRPC3; Endocrinology; Internal medicine; Cyclopiazonic acid; TRPC5; Transient receptor potential channel; TRPC1; TRPC6; Stretch-activated ion channel; Chemistry; Voltage-dependent calcium channel; Contraction (grammar); Extracellular; Vascular smooth muscle; Receptor; Biology; T-type calcium channel; Calcium; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001421054,0.000153258,0.0004201693,0.00005044445,0.00007762859,0.000004497208,0.00008096101,0.0002752079,0.0003816103],"category_scores_gemma":[0.00006213794,0.000120789,0.00003796923,0.00008366763,0.000905966,0.000092056,0.0001247324,0.0003415874,0.00000455489],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003948793,"about_ca_system_score_gemma":0.00002013784,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003971077,"about_ca_topic_score_gemma":0.000001557341,"domain_scores_codex":[0.9985107,0.0003585644,0.0004295754,0.0004428365,0.00005854064,0.0001998423],"domain_scores_gemma":[0.9991811,0.0004768283,0.0001345781,0.00007266788,0.00002632605,0.0001084803],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006832758,0.0004379957,0.0003503652,0.0000159044,0.000007343377,0.000002536089,0.001721899,0.0000667811,0.9957769,0.00001070244,0.0001651147,0.0007612107],"study_design_scores_gemma":[0.002122728,0.0006117115,0.00476746,0.00001909142,0.00001228264,0.000001377544,0.0003393742,0.003475417,0.9882545,0.0001609572,0.000109709,0.0001253506],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978912,0.0002802883,0.000002327883,0.00008043378,0.001453203,0.0002301079,0.00002695081,0.000009359375,0.00002612108],"genre_scores_gemma":[0.9988075,0.0003794038,0.000023081,0.0004577445,0.0002539055,0.00002172896,0.00001930041,0.000009304561,0.00002798816],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007522331,"threshold_uncertainty_score":0.4925631,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02999969713699554,"score_gpt":0.3447100053064482,"score_spread":0.3147103081694527,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}