{"id":"W2144133996","doi":"10.1128/aac.00155-09","title":"Influence of Tigecycline on Expression of Virulence Factors in Biofilm-Associated Cells of Methicillin-Resistant <i>Staphylococcus aureus</i>","year":2009,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antimicrobial Resistance in Staphylococcus","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Hospital for Sick Children; Wellcome Trust","keywords":"Biofilm; Microbiology; Biology; Staphylococcus aureus; Virulence; Tigecycline; Bacterial adhesin; Downregulation and upregulation; Staphylococcus epidermidis; Antimicrobial; Gene; Bacteria; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009992107,0.0002638851,0.0005450316,0.0002469459,0.0001764399,0.00050186,0.0000878591,0.0002566059,0.0007431843],"category_scores_gemma":[0.0001738676,0.0000979208,0.0002827829,0.0002823795,0.0001765622,0.0002045806,0.0001629589,0.000331307,0.0001716],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003832107,"about_ca_system_score_gemma":0.0003406295,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00147934,"about_ca_topic_score_gemma":0.001633427,"domain_scores_codex":[0.9998424,0.00001891141,0.00001395661,0.0000451845,0.00003993638,0.00003959832],"domain_scores_gemma":[0.9998937,0.00002716871,0.00002721908,0.000006094261,0.00001936667,0.00002662448],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004221365,0.00003116352,0.0006564872,0.00005596305,0.000005853832,0.00003218534,0.0000280256,0.00007172502,0.997579,0.0000124885,0.00003516579,0.001069797],"study_design_scores_gemma":[0.00002534547,0.001267836,0.08440403,0.00002714133,0.00006344135,0.0001716552,0.0003369954,0.001466593,0.9101797,0.00006487772,0.001970455,0.00002182956],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966972,0.001373239,0.0002649254,0.0000944228,0.00003011488,0.00001349475,0.0008353355,0.00002140132,0.0006700144],"genre_scores_gemma":[0.9954547,0.0009974058,0.001067764,0.0001379456,0.00001682931,0.00005223676,0.0009969827,0.00001402592,0.001262108],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00147934,"threshold_uncertainty_score":0.00294143,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0143001820701102,"score_gpt":0.2744974285994911,"score_spread":0.2601972465293809,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}