{"id":"W2144133996","doi":"10.1128/aac.00155-09","title":"Influence of Tigecycline on Expression of Virulence Factors in Biofilm-Associated Cells of Methicillin-Resistant <i>Staphylococcus aureus</i>","year":2009,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antimicrobial Resistance in Staphylococcus","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Hospital for Sick Children; Wellcome Trust","keywords":"Biofilm; Microbiology; Biology; Staphylococcus aureus; Virulence; Tigecycline; Bacterial adhesin; Downregulation and upregulation; Staphylococcus epidermidis; Antimicrobial; Gene; Bacteria; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002717551,0.0003258304,0.0009398828,0.0002673394,0.0000420604,0.000007031508,0.0002229974,0.0002776614,0.00003586548],"category_scores_gemma":[0.0000863845,0.0002664041,0.0001922977,0.0005028629,0.0003204788,0.00008233195,0.00002967292,0.0002696488,0.000001003796],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004745382,"about_ca_system_score_gemma":0.00008831752,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002043862,"about_ca_topic_score_gemma":0.00001755135,"domain_scores_codex":[0.997877,0.00007290469,0.0009455938,0.0004071934,0.000352354,0.0003449722],"domain_scores_gemma":[0.9984806,0.000130102,0.0006773209,0.0003877886,0.0002256466,0.0000985825],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001407522,0.001097043,0.03121338,0.0001900814,0.00004426081,0.000008932161,0.0005792512,0.0001789816,0.9638772,0.00002402283,0.0009618005,0.0004175108],"study_design_scores_gemma":[0.002010338,0.0005598052,0.2341734,0.00132178,0.00002851035,1.71269e-7,0.00004243056,0.00001039226,0.7613168,0.00003552386,0.0003356617,0.0001651033],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986607,0.00006722123,0.00001983375,0.0003905018,0.00003920074,0.0005014332,0.000158243,0.00001903254,0.0001438318],"genre_scores_gemma":[0.9958882,0.001686446,0.0004685627,0.001823491,0.00001600894,0.000001438004,0.00002018554,0.00002737363,0.00006833195],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2029601,"threshold_uncertainty_score":0.9999788,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0143001820701102,"score_gpt":0.2744974285994911,"score_spread":0.2601972465293809,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}