{"id":"W2144149966","doi":"10.1016/j.bbamcr.2013.04.011","title":"Salinomycin induces activation of autophagy, mitophagy and affects mitochondrial polarity: Differences between primary and cancer cells","year":2013,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":145,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"Linköpings Universitet; Cancerfonden","keywords":"Salinomycin; Autophagy; Mitophagy; Cell biology; Mitochondrion; Cancer cell; Wnt signaling pathway; Biology; Cancer stem cell; Apoptosis; Context (archaeology); Cancer research; Chemistry; Stem cell; Cancer; Biochemistry; Signal transduction; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004409768,0.0001801913,0.0002278438,0.0001556191,0.0001395484,0.0001741483,0.00006518637,0.0002022073,0.0008337148],"category_scores_gemma":[0.00005588572,0.00006195076,0.0002115458,0.000168104,0.0000924273,0.0001262762,0.00009573928,0.0002316592,0.0001975186],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002823951,"about_ca_system_score_gemma":0.000126214,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008231084,"about_ca_topic_score_gemma":0.001221658,"domain_scores_codex":[0.9999425,0.000006305838,0.000007417831,0.0000160417,0.00001399852,0.00001375706],"domain_scores_gemma":[0.9999553,0.000007398716,0.000009717287,0.000006013037,0.000006471986,0.00001506419],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001448111,0.00001162327,0.0002953378,0.00003471875,0.000004103096,0.00007855162,0.00001345624,0.00001717242,0.9983553,0.00003198088,0.00003209227,0.0009808788],"study_design_scores_gemma":[0.000008527731,0.0002087044,0.01559886,0.000003039537,0.00001263962,0.0003727615,0.0000266539,0.0001496353,0.9812481,0.00002581963,0.002342757,0.000002515461],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988771,0.006569167,0.001293556,0.0001085227,0.00003109772,0.00003110884,0.001004053,0.00006108417,0.002130319],"genre_scores_gemma":[0.9943802,0.002269198,0.0007353189,0.0000576318,0.00001199866,0.00003272326,0.0007572116,0.000007626586,0.001748138],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008337148,"threshold_uncertainty_score":0.00278908,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03283342492425775,"score_gpt":0.3236690386424312,"score_spread":0.2908356137181735,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}