{"id":"W2144154171","doi":"10.2353/ajpath.2006.051208","title":"Up-Regulation of Cation-Independent Mannose 6-Phosphate Receptor and Endosomal-Lysosomal Markers in Surviving Neurons after 192-IgG-Saporin Administrations into the Adult Rat Brain","year":2006,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta; McGill University","funders":"Fondation pour la Recherche Médicale; Alzheimer Society","keywords":"Endosome; Mannose receptor; Mannose 6-phosphate; Saporin; Mannose; Internal medicine; Endocrinology; Receptor; Chemistry; Biology; Neuroscience; Cell biology; Medicine; Immunology; Biochemistry; Antibody; Immunotoxin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001519109,0.0004408316,0.000570154,0.0003543,0.0002676997,0.0004319044,0.0003318125,0.0004311308,0.001595903],"category_scores_gemma":[0.0001447701,0.000197851,0.0003991357,0.0002010352,0.0003992784,0.0005599599,0.0002264096,0.001131793,0.0003026772],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000599627,"about_ca_system_score_gemma":0.0005511049,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002648044,"about_ca_topic_score_gemma":0.003334257,"domain_scores_codex":[0.9998633,0.000006404004,0.00001045439,0.00002459797,0.00002411247,0.00007110337],"domain_scores_gemma":[0.9998143,0.0000288625,0.00003484571,0.00001442747,0.00002711593,0.0000804841],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003167044,0.00003193642,0.0002607633,0.00004409042,0.00001232747,0.0001872042,0.00005128773,0.00002722271,0.9978645,0.0001587448,0.00002877151,0.001016425],"study_design_scores_gemma":[0.00001843471,0.0003314334,0.006682753,0.000006908204,0.00004924246,0.0002536977,0.0001231462,0.0003259712,0.9915826,0.00008418597,0.0005356999,0.000005832973],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963155,0.00143731,0.0008586159,0.00006222219,0.00003341308,0.000007826081,0.0002080837,0.00005963017,0.001017488],"genre_scores_gemma":[0.9915963,0.0009629558,0.001138497,0.00003536849,0.00001664282,0.00002893527,0.0004228643,0.00002790267,0.005770552],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002648044,"threshold_uncertainty_score":0.005338848,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004579913196469603,"score_gpt":0.2502191984337994,"score_spread":0.2456392852373298,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}