{"id":"W2144190487","doi":"10.1345/aph.1a447","title":"Interactions between Recreational Drugs and Antiretroviral Agents","year":2002,"lang":"en","type":"review","venue":"Annals of Pharmacotherapy","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":137,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Toronto General Hospital; St. Michael's Hospital","funders":"","keywords":"Medicine; Nelfinavir; Pharmacology; Methadone; Nevirapine; Ritonavir; Drug interaction; Recreational Drug; Drug; CYP2D6; Mephedrone; Cytochrome P450; Human immunodeficiency virus (HIV); Internal medicine; Virology; Viral load; Antiretroviral therapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001057442,0.0004280289,0.001306983,0.003894486,0.0003429943,0.000847156,0.0005700258,0.0007422384,0.01108625],"category_scores_gemma":[0.006924252,0.0001927837,0.001334604,0.006310682,0.0002577365,0.001246037,0.0004588753,0.000472617,0.000844545],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006085879,"about_ca_system_score_gemma":0.00113017,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001331427,"about_ca_topic_score_gemma":0.003873431,"domain_scores_codex":[0.9980604,0.0004814937,0.0008478521,0.0001255728,0.0004189606,0.00006578593],"domain_scores_gemma":[0.9915242,0.005126996,0.002806595,0.00009349393,0.0003889365,0.00005964991],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002588487,0.0002775605,0.08350496,0.2300667,0.004540909,0.01010352,0.000513386,0.0006648016,0.001656758,0.001293431,0.01676637,0.6480232],"study_design_scores_gemma":[0.0008719481,0.002311282,0.3217879,0.1919397,0.01848107,0.06423738,0.001235047,0.001129264,0.003091779,0.002758873,0.3919721,0.0001836757],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01648528,0.9728377,0.0003989676,0.0008537648,0.0001332029,0.0001458974,0.003396631,0.00002161386,0.005726991],"genre_scores_gemma":[0.1140532,0.8765886,0.002360492,0.001466839,0.0006669636,0.0002638151,0.003590698,0.000009792791,0.000999621],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01108625,"threshold_uncertainty_score":0.0370872,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2417025215372811,"score_gpt":0.4834954928240249,"score_spread":0.2417929712867438,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}