{"id":"W2144240328","doi":"10.1089/scd.2011.0214","title":"Generation of Neural Stem Cells from Embryonic Stem Cells Using the Default Mechanism: In Vitro and In Vivo Characterization","year":2011,"lang":"en","type":"article","venue":"Stem Cells and Development","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; National Science Council","keywords":"Biology; Neurosphere; Neural stem cell; Embryonic stem cell; Stem cell; Cell biology; Population; Progenitor cell; Cellular differentiation; Induced pluripotent stem cell; Neural development; Neural cell; Adult stem cell; Neuroscience; Cell; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001572133,0.0001930658,0.0001981827,0.0001983127,0.0001095657,0.0002913765,0.0001996768,0.0001758565,0.0004337045],"category_scores_gemma":[0.0001327688,0.0001193107,0.0001248856,0.0001362858,0.0001824925,0.000142327,0.0001542193,0.0003180214,0.0002623689],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000161328,"about_ca_system_score_gemma":0.0001879019,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004237427,"about_ca_topic_score_gemma":0.0007691064,"domain_scores_codex":[0.9998968,0.000008242871,0.00001866615,0.00001808624,0.00004789118,0.00001023589],"domain_scores_gemma":[0.9999216,0.0000151108,0.00001709372,0.00001648173,0.00001458246,0.00001519538],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002174981,0.00001336905,0.0004578186,0.00002832539,0.000002178218,0.00004677226,0.0000238561,0.00013012,0.9970692,0.0001662678,0.00001215143,0.002028198],"study_design_scores_gemma":[0.00000568389,0.0001025474,0.003043687,0.000007176673,0.00001161432,0.0002541181,0.0000231909,0.001115605,0.9934968,0.00007632222,0.001860303,0.000002994172],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9650113,0.0009829829,0.03099162,0.0000358455,0.00002055345,0.0001347256,0.0006555407,0.00008598626,0.002081433],"genre_scores_gemma":[0.9674896,0.001290826,0.02692879,0.00003812025,0.000006534918,0.0001295862,0.001564395,0.00002924409,0.002522822],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004337045,"threshold_uncertainty_score":0.001450896,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04490909493457605,"score_gpt":0.2391846499287429,"score_spread":0.1942755549941668,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}