{"id":"W2144305967","doi":"10.1093/glycob/cwq085","title":"Over-expression of ST3Gal-I promotes mammary tumorigenesis","year":2010,"lang":"en","type":"article","venue":"Glycobiology","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":144,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"National Institute for Health and Care Research; Cancer Research UK; Mayo Clinic","keywords":"Sialyltransferase; Carcinogenesis; Glycosylation; Mucin; Genetically modified mouse; Sialic acid; MUC1; Biology; Mammary tumor; Cancer research; Mammary gland; Transgene; Glycoprotein; Sialyl-Lewis X; Breast cancer; Cancer; Molecular biology; Biochemistry; Immunology; Gene; Inflammation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001657906,0.0003692633,0.0002607435,0.000373385,0.0001109646,0.0003577673,0.0001958494,0.0002944034,0.001183917],"category_scores_gemma":[0.0001526847,0.0001845134,0.0002319766,0.0003000563,0.0002769431,0.0001839033,0.000323578,0.0008460114,0.0004211889],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004734166,"about_ca_system_score_gemma":0.0003221019,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001101927,"about_ca_topic_score_gemma":0.001016248,"domain_scores_codex":[0.9998,0.00002776423,0.00001441281,0.00003498693,0.0000641439,0.00005868883],"domain_scores_gemma":[0.9996498,0.00007649522,0.00009152005,0.0000307202,0.00001618971,0.0001352625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001124374,0.00003877034,0.0001400799,0.00001115638,0.000003144628,0.00003029538,0.00001106088,0.00005325166,0.9988697,0.0000811767,0.00004029594,0.0006086366],"study_design_scores_gemma":[0.00001874201,0.0005146294,0.005045755,0.000005753337,0.00001334883,0.0001927639,0.00003202066,0.001125226,0.9906594,0.00007668074,0.002311225,0.000004508552],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934933,0.001392328,0.002026237,0.0001422739,0.00003600617,0.00002245173,0.0004400542,0.000268887,0.002178591],"genre_scores_gemma":[0.9938968,0.001013109,0.001292143,0.00007161876,0.00001466358,0.00002195897,0.0005933053,0.00004941051,0.003046957],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001183917,"threshold_uncertainty_score":0.003960609,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007203245870345084,"score_gpt":0.2663893213658331,"score_spread":0.259186075495488,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}