{"id":"W2144318479","doi":"10.4049/jimmunol.169.10.5660","title":"Differential Regulation of CD44 Expression by Lipopolysaccharide (LPS) and TNF-α in Human Monocytic Cells: Distinct Involvement of c-Jun N-Terminal Kinase in LPS-Induced CD44 Expression","year":2002,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada; University of British Columbia; Children's Hospital of Eastern Ontario; Vancouver Hospital and Health Sciences Centre; University of British Columbia Hospital; University of Ottawa","funders":"Ontario HIV Treatment Network; Natural Sciences and Engineering Research Council of Canada; Medical Research Council Canada; Cancer Research Society; Medical Research Council; University of Ottawa","keywords":"Lipopolysaccharide; Terminal (telecommunication); Cell biology; CD44; Tumor necrosis factor alpha; Kinase; Expression (computer science); THP1 cell line; Chemistry; Molecular biology; Biology; Immunology; Cell culture; Cell; Biochemistry; Computer science; Telecommunications; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000130706,0.0002088751,0.0001794647,0.0002297808,0.0001865905,0.00031462,0.00005842265,0.0001760612,0.0007956916],"category_scores_gemma":[0.0001231665,0.0001558584,0.000240205,0.0002367411,0.0001446949,0.0001750562,0.0001348128,0.0002948461,0.0003231563],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002158208,"about_ca_system_score_gemma":0.0002248842,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005186984,"about_ca_topic_score_gemma":0.000683819,"domain_scores_codex":[0.9998173,0.00003134313,0.00001723827,0.00002224732,0.00005514452,0.00005660783],"domain_scores_gemma":[0.9999204,0.00001162068,0.00001712251,0.000009269235,0.00001943828,0.00002217365],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001557847,0.00001581472,0.0003132891,0.00002790502,0.00000193668,0.00004858179,0.00002667217,0.00001339011,0.9987895,0.00003492212,0.0000100326,0.0005622344],"study_design_scores_gemma":[0.00004157589,0.0004976297,0.03727835,0.00001556714,0.00002741721,0.000556014,0.0001321889,0.001039257,0.9579775,0.00007398059,0.002350891,0.000009612714],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955502,0.001538681,0.0017964,0.00005791561,0.000021395,0.00003302885,0.0002770916,0.00001411378,0.0007114077],"genre_scores_gemma":[0.9917121,0.001934027,0.003914307,0.00005623616,0.0000178941,0.00008826409,0.0006029766,0.000006208812,0.00166814],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007956916,"threshold_uncertainty_score":0.002661884,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01708791587012322,"score_gpt":0.2369125285080119,"score_spread":0.2198246126378887,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}