{"id":"W2144318479","doi":"10.4049/jimmunol.169.10.5660","title":"Differential Regulation of CD44 Expression by Lipopolysaccharide (LPS) and TNF-α in Human Monocytic Cells: Distinct Involvement of c-Jun N-Terminal Kinase in LPS-Induced CD44 Expression","year":2002,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada; University of British Columbia; Children's Hospital of Eastern Ontario; Vancouver Hospital and Health Sciences Centre; University of British Columbia Hospital; University of Ottawa","funders":"Ontario HIV Treatment Network; Natural Sciences and Engineering Research Council of Canada; Medical Research Council Canada; Cancer Research Society; Medical Research Council; University of Ottawa","keywords":"Lipopolysaccharide; Terminal (telecommunication); Cell biology; CD44; Tumor necrosis factor alpha; Kinase; Expression (computer science); THP1 cell line; Chemistry; Molecular biology; Biology; Immunology; Cell culture; Cell; Biochemistry; Computer science; Telecommunications; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006523407,0.0002027932,0.0005540374,0.0004343153,0.0001057875,0.000006786869,0.0003324011,0.0002967077,0.0003316096],"category_scores_gemma":[0.0000902202,0.0001451805,0.00008810822,0.0001217321,0.0002634524,0.0002138573,0.00015763,0.0005077288,0.000005351163],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008868128,"about_ca_system_score_gemma":0.00003096667,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001988114,"about_ca_topic_score_gemma":0.00002362343,"domain_scores_codex":[0.9972088,0.001049636,0.001226248,0.0001494974,0.00008906829,0.0002767399],"domain_scores_gemma":[0.9981753,0.0002686571,0.001142655,0.0003034972,0.00009397887,0.00001588723],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00171111,0.0003340831,0.0005940408,0.00003800079,0.00005605008,0.000007228569,0.002394297,0.00001427756,0.9902598,0.00003634154,0.0001642664,0.004390478],"study_design_scores_gemma":[0.003422288,0.0008512624,0.01390284,0.000464526,0.00005036235,0.00009350811,0.0007591739,0.00004069497,0.9800506,0.000166374,0.00007411178,0.0001242405],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951296,0.004088922,0.0001155669,0.0000988263,0.0003136875,0.0002138665,0.000003982184,0.000005330744,0.00003021747],"genre_scores_gemma":[0.999092,0.0006649888,0.00002179678,0.000008944094,0.00002130378,0.000005533975,0.0000132331,0.00001370821,0.0001584224],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0133088,"threshold_uncertainty_score":0.5920289,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01708791587012322,"score_gpt":0.2369125285080119,"score_spread":0.2198246126378887,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}