{"id":"W2144379375","doi":"10.1128/iai.73.10.6736-6741.2005","title":"Isocitrate Lyase Activity Is Required for Virulence of the Intracellular Pathogen <i>Rhodococcus equi</i>","year":2005,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Infectious Disease Case Reports and Treatments","field":"Medicine","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Health Research Board","keywords":"Rhodococcus equi; Virulence; Biology; Isocitrate lyase; Microbiology; Pathogen; Intracellular; Human pathogen; Rhodococcus; Virology; Bacteria; Biochemistry; Enzyme; Genetics; Gene; Glyoxylate cycle","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002336175,0.0001223396,0.0001935401,0.00003938152,0.0002681178,0.00001560698,0.00002495809,0.00007982353,0.00007160507],"category_scores_gemma":[0.00009179184,0.00008546323,0.0001701209,0.0001210801,0.0001079196,0.0001321049,0.00003566122,0.0001287726,0.000004429728],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007730328,"about_ca_system_score_gemma":0.00009007582,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005055484,"about_ca_topic_score_gemma":0.00002627497,"domain_scores_codex":[0.9993381,0.00007234875,0.0001922509,0.0001434816,0.0001076714,0.0001461558],"domain_scores_gemma":[0.9992602,0.00004541735,0.0001657696,0.0003080656,0.0001441906,0.00007628121],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008202581,0.00303383,0.2189161,0.0005152614,0.0006072409,0.00002261728,0.001030469,0.00001952186,0.6107423,0.0003366941,0.0007232792,0.1632325],"study_design_scores_gemma":[0.004356054,0.0008184516,0.3999659,0.0001723233,0.0007370621,0.000347876,0.00005205174,0.0008959574,0.5605728,0.0005104084,0.03129059,0.0002805804],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965805,0.0002287575,0.0004492859,0.0002832391,0.0001459761,0.0006212238,0.0000535414,0.00003752507,0.001599899],"genre_scores_gemma":[0.9989047,0.000220204,0.00004879459,0.0003881231,0.00006859074,0.00004518976,0.00001038394,0.00001169447,0.0003023076],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1810498,"threshold_uncertainty_score":0.3485089,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0238560542304231,"score_gpt":0.2912029824944653,"score_spread":0.2673469282640422,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}