{"id":"W2144379375","doi":"10.1128/iai.73.10.6736-6741.2005","title":"Isocitrate Lyase Activity Is Required for Virulence of the Intracellular Pathogen <i>Rhodococcus equi</i>","year":2005,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Infectious Disease Case Reports and Treatments","field":"Medicine","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Health Research Board","keywords":"Rhodococcus equi; Virulence; Biology; Isocitrate lyase; Microbiology; Pathogen; Intracellular; Human pathogen; Rhodococcus; Virology; Bacteria; Biochemistry; Enzyme; Genetics; Gene; Glyoxylate cycle","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001423492,0.0001685902,0.0002200488,0.0001794893,0.0001710307,0.0002934461,0.0001384055,0.0004369679,0.001064523],"category_scores_gemma":[0.0005884155,0.00007705347,0.0001031867,0.00009734887,0.000398499,0.0002090588,0.0001374852,0.0002958776,0.0002934251],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003280493,"about_ca_system_score_gemma":0.0002026323,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001156236,"about_ca_topic_score_gemma":0.0007633217,"domain_scores_codex":[0.99985,0.00002957637,0.00001743672,0.00003355363,0.00003638199,0.000033097],"domain_scores_gemma":[0.9997916,0.00005079352,0.00008036108,0.00002177621,0.00002663623,0.00002896914],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006042281,0.0002116074,0.0332074,0.0001568798,0.00001166919,0.02015895,0.0003667255,0.0001307235,0.932575,0.0006922711,0.0002589937,0.01162567],"study_design_scores_gemma":[0.00006808974,0.001647347,0.1862674,0.00005576849,0.00006750151,0.1994848,0.0008373795,0.001411321,0.5983686,0.0004377179,0.01132677,0.00002722245],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975584,0.0007714938,0.0002882539,0.000130828,0.00000573991,0.000007158983,0.00002780425,0.00001081528,0.001199507],"genre_scores_gemma":[0.9991261,0.0002011641,0.0002303197,0.0000208218,0.000005005038,0.000002885439,0.00004743524,0.00000338335,0.0003628664],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001156236,"threshold_uncertainty_score":0.003561139,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0238560542304231,"score_gpt":0.2912029824944653,"score_spread":0.2673469282640422,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}