{"id":"W2144473770","doi":"10.1093/hmg/ddp299","title":"Inactive X chromosome-specific reduction in placental DNA methylation","year":2009,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":80,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Methylation; CpG site; Biology; DNA methylation; Promoter; Placenta; Intergenic region; Molecular biology; X-inactivation; Andrology; Genetics; Gene; X chromosome; Genome; Gene expression; Fetus; Pregnancy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002018027,0.0002232558,0.0001677561,0.0001502854,0.00009647025,0.00004247688,0.0001637456,0.0002299558,0.00002540953],"category_scores_gemma":[0.00001830978,0.0002640744,0.00009527351,0.0002062581,0.00005843097,0.000006179775,0.00004710012,0.0001438581,0.0000119739],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007461553,"about_ca_system_score_gemma":0.00003678775,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004625598,"about_ca_topic_score_gemma":0.00001270373,"domain_scores_codex":[0.9985002,0.0001312252,0.0003402155,0.0004983583,0.0002302849,0.0002997667],"domain_scores_gemma":[0.9992766,0.000003996961,0.0001222217,0.0004198707,0.00008880744,0.00008848857],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003617574,0.0001170055,0.0002748735,0.000003422867,0.00001228931,0.000007858189,0.00009994066,0.001342998,0.9906555,0.0004340896,0.00007082116,0.006944986],"study_design_scores_gemma":[0.0007065147,0.0005411805,0.03283744,0.00001187685,0.00001164091,0.000006234696,0.00006797648,0.00007427437,0.9584348,0.002857088,0.004149128,0.0003018281],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882821,0.004073258,0.004436126,0.00006788045,0.0001401209,0.0003233298,0.000005392395,0.00001759049,0.002654195],"genre_scores_gemma":[0.9975401,0.0006131224,0.001181367,0.00006205943,0.0002256087,0.00001287353,0.0002388658,0.000032118,0.00009393087],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03256257,"threshold_uncertainty_score":0.9999812,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01489718146457746,"score_gpt":0.2766389256808927,"score_spread":0.2617417442163152,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}