{"id":"W2144474352","doi":"10.1128/jb.183.20.5885-5895.2001","title":"In Vivo Synthesis of the Periplasmic Domain of TonB Inhibits Transport through the FecA and FhuA Iron Siderophore Transporters of <i>Escherichia coli</i>","year":2001,"lang":"en","type":"article","venue":"Journal of Bacteriology","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Regina","funders":"Canadian Institutes of Health Research; Deutsche Forschungsgemeinschaft","keywords":"Periplasmic space; Ferrichrome; Colicin; Bacterial outer membrane; Biology; Siderophore; Escherichia coli; Chemiosmosis; Cytoplasm; Enterobactin; Transport protein; Membrane transport protein; Biochemistry; Signal peptide; Permease; Membrane protein; Biophysics; Peptide sequence; Membrane; Gene; ATP synthase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003282922,0.0001615405,0.0004997885,0.00005198045,0.00002896603,0.000002555641,0.0003408988,0.0003489465,0.00002850562],"category_scores_gemma":[0.00004026254,0.00009853584,0.0001865921,0.0001459445,0.0006248129,0.000007151164,0.00004503605,0.0001985947,7.317325e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009447225,"about_ca_system_score_gemma":0.0001085316,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006993907,"about_ca_topic_score_gemma":0.0001928651,"domain_scores_codex":[0.9986007,0.0001395557,0.0007891558,0.00016429,0.0001166993,0.000189619],"domain_scores_gemma":[0.9988825,0.00003777546,0.0006634392,0.0002666981,0.0001188292,0.00003072305],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000655102,0.00008894315,0.01055457,0.00004512057,0.00006990615,0.000006913432,0.0003352544,0.00002706628,0.9877982,0.00004554897,0.000048163,0.0003252784],"study_design_scores_gemma":[0.000724779,0.0008283147,0.05382098,0.00006524551,0.00006684032,0.0001892294,0.0003473466,0.000001407939,0.9336069,0.0001508785,0.01009574,0.0001022936],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997344,0.000528613,0.0000405987,0.001556916,0.0002286165,0.000143358,0.00004662551,9.552647e-7,0.0001103339],"genre_scores_gemma":[0.9970966,0.002198662,0.000422991,0.0001721045,0.00006378294,0.000003217602,0.00000213544,0.00001394951,0.00002654592],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05419119,"threshold_uncertainty_score":0.4018175,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005603655317028888,"score_gpt":0.2045785031640717,"score_spread":0.1989748478470428,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}