{"id":"W2144523137","doi":"10.1093/hmg/ddt670","title":"Drebrin E depletion in human intestinal epithelial cells mimics Rab8a loss of function","year":2014,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Centre National de la Recherche Scientifique; Ligue Contre le Cancer; Agence Nationale de la Recherche; McGill University; Aix-Marseille Université; Association pour la Recherche sur le Cancer","keywords":"Biology; Cell biology; Compartment (ship); Myosin; Intracellular; Endocytosis; Brush border; Actin; Apical cell; Intestinal mucosa; Cell; Biochemistry; Vesicle; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001426295,0.0002931433,0.0003816383,0.0003019486,0.000214932,0.0003578253,0.0002567312,0.0005492276,0.002568066],"category_scores_gemma":[0.0001246735,0.0002541886,0.0002945876,0.0002891449,0.0002133275,0.0002522413,0.0002935416,0.0005140329,0.001270357],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002702139,"about_ca_system_score_gemma":0.0001347132,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006039343,"about_ca_topic_score_gemma":0.0008271088,"domain_scores_codex":[0.999786,0.00002945597,0.00003002416,0.00005651748,0.00004585602,0.00005215042],"domain_scores_gemma":[0.9999087,0.00001567942,0.00002095674,0.00002163644,0.000009293664,0.00002365835],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001058532,0.00001846514,0.00009383017,0.00002468003,0.000003023902,0.00009671426,0.000009985279,0.00002579641,0.999266,0.00003543659,0.00003122554,0.0002889316],"study_design_scores_gemma":[0.00003897843,0.0002946541,0.00918838,0.000008415122,0.00001938165,0.0007155365,0.00006960854,0.0009475608,0.9847528,0.0000405179,0.003916304,0.000007893336],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917819,0.002202357,0.002407893,0.0001748499,0.00003631253,0.00004598817,0.001359264,0.0002230998,0.001768277],"genre_scores_gemma":[0.9904692,0.001058521,0.002096967,0.0001266685,0.000007923438,0.00009681191,0.001838057,0.00003976512,0.004266243],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002568066,"threshold_uncertainty_score":0.008591056,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008301292676297633,"score_gpt":0.2212580112805979,"score_spread":0.2129567186043002,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}