{"id":"W2144640625","doi":"10.1046/j.1365-2958.2001.02532.x","title":"The LuxS family of bacterial autoinducers: biosynthesis of a novel quorum‐sensing signal molecule","year":2001,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1024,"is_retracted":false,"has_abstract":true,"ca_institutions":"Calgary General Hospital; University of Calgary","funders":"Office of Naval Research; Deutscher Akademischer Austauschdienst; National Science Foundation","keywords":"Autoinducer; Vibrio harveyi; Quorum sensing; Homoserine; Biology; Bacteria; Vibrio; Biochemistry; Microbiology; Biosynthesis; Escherichia coli; Gene; Genetics; Virulence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001169212,0.0005811756,0.0003451484,0.0004914004,0.0002861316,0.0004838989,0.0003372067,0.0004005853,0.001119711],"category_scores_gemma":[0.00009936266,0.0001299827,0.0002432289,0.0004545329,0.0004018088,0.000440142,0.0004734536,0.0004669602,0.0008980634],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003579007,"about_ca_system_score_gemma":0.0003598694,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000506998,"about_ca_topic_score_gemma":0.0004064886,"domain_scores_codex":[0.9998247,0.00002197113,0.000008892925,0.00003942203,0.00007050265,0.00003441928],"domain_scores_gemma":[0.9999257,0.000005226006,0.00002674193,0.000005939419,0.00001615672,0.00002019966],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001892527,0.00003847759,0.001180054,0.0002933823,0.0000121491,0.0003319971,0.0001016028,0.0001891197,0.9575352,0.002654048,0.00125765,0.03621706],"study_design_scores_gemma":[0.00009865639,0.001190068,0.02512716,0.0001079065,0.0000566314,0.005202279,0.0003217561,0.003386704,0.6462134,0.00440762,0.3138011,0.00008677476],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7426283,0.09830087,0.1143508,0.002208199,0.0009175619,0.0004161423,0.005038233,0.004770048,0.03136978],"genre_scores_gemma":[0.9060731,0.02057162,0.03675595,0.0008508639,0.0004686428,0.0002033588,0.006017663,0.000153944,0.02890478],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001119711,"threshold_uncertainty_score":0.003745794,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01056533843837009,"score_gpt":0.2173571328685131,"score_spread":0.206791794430143,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}