{"id":"W2144695459","doi":"10.1128/jb.185.18.5563-5572.2003","title":"A Dual Binding Site for Integration Host Factor and the Response Regulator CtrA inside the <i>Caulobacter crescentus</i> Replication Origin","year":2003,"lang":"en","type":"article","venue":"Journal of Bacteriology","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Caulobacter crescentus; Biology; Origin of replication; DNA replication; Binding site; Plasmid; DNA-binding protein; Genetics; Cell cycle; Transcription factor; DNA; Molecular biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00121294,0.0001510255,0.0002418198,0.00006366669,0.0001424481,0.00005500371,0.0001697809,0.0002880393,0.000009298994],"category_scores_gemma":[0.0009875816,0.0000810502,0.0001271939,0.0000721062,0.0003075283,0.000008679417,0.0000533529,0.0001971806,0.000001773145],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000232048,"about_ca_system_score_gemma":0.0001129702,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000270985,"about_ca_topic_score_gemma":0.00001544158,"domain_scores_codex":[0.9986081,0.0004435941,0.000447098,0.0002325902,0.00006636106,0.0002022966],"domain_scores_gemma":[0.9987466,0.0001532638,0.0004665876,0.0003953916,0.0001885024,0.00004964444],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00312341,0.00001887673,0.00050509,0.000003911554,0.00006050572,0.000001112407,0.00008079408,5.928458e-7,0.9942255,0.0003437697,0.0005285685,0.001107858],"study_design_scores_gemma":[0.002617741,0.001289172,0.0269439,0.00002000075,0.00006678604,0.0007340155,0.0001060169,0.0000140005,0.6315411,0.0002237792,0.3362737,0.0001697984],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940621,0.0004065447,0.0007339621,0.003915924,0.0004939109,0.0003244097,0.0000465336,0.000004009061,0.00001259235],"genre_scores_gemma":[0.997582,0.0005739615,0.000793272,0.0005314401,0.000334425,0.00001508536,0.0000230885,0.00001598159,0.0001307673],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3626844,"threshold_uncertainty_score":0.3305131,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0124802109959386,"score_gpt":0.25298191358364,"score_spread":0.2405017025877014,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}