{"id":"W2144710665","doi":"10.1093/jn/137.3.548","title":"(n-3) PUFA Alter Raft Lipid Composition and Decrease Epidermal Growth Factor Receptor Levels in Lipid Rafts of Human Breast Cancer Cells1,2","year":2007,"lang":"en","type":"article","venue":"Journal of Nutrition","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":278,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Lipid raft; Docosahexaenoic acid; Ceramide; Eicosapentaenoic acid; Chemistry; Sphingomyelin; MAPK/ERK pathway; Diacylglycerol kinase; Epidermal growth factor; p38 mitogen-activated protein kinases; Endocrinology; Phosphorylation; Internal medicine; Apoptosis; Biochemistry; Signal transduction; Cholesterol; Polyunsaturated fatty acid; Fatty acid; Biology; Receptor; Protein kinase C; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001408377,0.000325686,0.0003597003,0.0003922108,0.0003686239,0.0004003633,0.0003212821,0.00037419,0.002000396],"category_scores_gemma":[0.0002257592,0.0002639994,0.0004159129,0.0003197549,0.000180462,0.0002498537,0.0002376088,0.0005282674,0.0007667087],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004101723,"about_ca_system_score_gemma":0.0002456349,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003088676,"about_ca_topic_score_gemma":0.003733001,"domain_scores_codex":[0.9998502,0.00002239289,0.0000117144,0.00002102331,0.00004257515,0.00005216746],"domain_scores_gemma":[0.9999065,0.00002559742,0.00001651901,0.00001546291,0.00002016124,0.00001571345],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004659734,0.00003197469,0.0002457154,0.00002626228,0.0000115619,0.00003864066,0.00001529261,0.00003236434,0.9980697,0.00003247899,0.000075992,0.0009541414],"study_design_scores_gemma":[0.0000328564,0.000148689,0.004799072,0.000003345848,0.00002752648,0.0002656755,0.00005296773,0.0002261743,0.9926339,0.00004321452,0.001761747,0.000004817423],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915339,0.003375709,0.001738202,0.0003311334,0.00007026643,0.00003621065,0.001256566,0.00009818998,0.001559945],"genre_scores_gemma":[0.98906,0.002755628,0.001974106,0.0001872918,0.00003005874,0.00008524862,0.001909667,0.00005488822,0.00394299],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003088676,"threshold_uncertainty_score":0.006691992,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01475781343390898,"score_gpt":0.2773123324370534,"score_spread":0.2625545190031445,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}