{"id":"W2144710665","doi":"10.1093/jn/137.3.548","title":"(n-3) PUFA Alter Raft Lipid Composition and Decrease Epidermal Growth Factor Receptor Levels in Lipid Rafts of Human Breast Cancer Cells1,2","year":2007,"lang":"en","type":"article","venue":"Journal of Nutrition","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":278,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Lipid raft; Docosahexaenoic acid; Ceramide; Eicosapentaenoic acid; Chemistry; Sphingomyelin; MAPK/ERK pathway; Diacylglycerol kinase; Epidermal growth factor; p38 mitogen-activated protein kinases; Endocrinology; Phosphorylation; Internal medicine; Apoptosis; Biochemistry; Signal transduction; Cholesterol; Polyunsaturated fatty acid; Fatty acid; Biology; Receptor; Protein kinase C; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005114239,0.0001350401,0.0002804371,0.0001854606,0.00005010793,0.00001783141,0.00009454045,0.0001417736,0.00006017974],"category_scores_gemma":[0.0000416965,0.0001268248,0.0001110948,0.00009342907,0.00005501075,0.00003005844,0.00002825226,0.000153722,4.796373e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000304638,"about_ca_system_score_gemma":0.00004690863,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005151519,"about_ca_topic_score_gemma":0.00001633687,"domain_scores_codex":[0.9987963,0.00009495312,0.0005740132,0.0001558051,0.0001787202,0.0002001585],"domain_scores_gemma":[0.999068,0.00003135687,0.0003815523,0.00008739274,0.000266151,0.0001655685],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004388242,0.0003352119,0.008182768,0.0001003275,0.00003093196,0.000006577993,0.00009931691,0.000005952827,0.9892575,0.00001711725,0.0003683896,0.001157101],"study_design_scores_gemma":[0.002963195,0.00019367,0.07646707,0.0003013365,0.00003478012,0.0001392018,0.00008280834,0.000009247718,0.9189578,0.00004556182,0.0006593342,0.0001460372],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970109,0.00137583,0.0008565314,0.0002477118,0.0002867039,0.0001209721,0.00007843265,0.000002489365,0.0000204591],"genre_scores_gemma":[0.9960109,0.000955501,0.0009087736,0.0001689773,0.001896324,0.000002929036,0.000032392,0.00001563592,0.000008591212],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07029972,"threshold_uncertainty_score":0.5171766,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01475781343390898,"score_gpt":0.2773123324370534,"score_spread":0.2625545190031445,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}