{"id":"W2144800425","doi":"10.1210/jcem.86.12.8122","title":"Neuroactive Ring A-Reduced Metabolites of Progesterone in Human Plasma during Pregnancy: Elevated Levels of 5α-Dihydroprogesterone in Depressed Patients during the Latter Half of Pregnancy","year":2001,"lang":"en","type":"article","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Neuroendocrine regulation and behavior","field":"Psychology","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Pregnenolone; Endocrinology; Internal medicine; Metabolite; Pregnancy; Allopregnanolone; Neuroactive steroid; Pregnanolone; Gestation; Follicular phase; Medicine; Chemistry; Biology; Steroid; Hormone; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005121452,0.0003673584,0.001727773,0.0005435288,0.00007297371,0.000008929185,0.000930454,0.0001462985,0.0001391415],"category_scores_gemma":[0.0003884276,0.0002393868,0.0003729381,0.0005796432,0.0006083337,0.0002830852,0.0002530905,0.001280058,0.000002845349],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002130737,"about_ca_system_score_gemma":0.00005962753,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000104715,"about_ca_topic_score_gemma":0.00005687042,"domain_scores_codex":[0.992266,0.002260957,0.003900463,0.0003828286,0.0005045083,0.0006852587],"domain_scores_gemma":[0.9947783,0.0008281202,0.003142035,0.0007740944,0.0003750802,0.0001023555],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002020416,0.002858158,0.7222746,0.000112054,0.0004210394,0.0002717946,0.001743658,0.0002240673,0.2632116,0.0003619989,0.00000206357,0.006498533],"study_design_scores_gemma":[0.009489334,0.0002745659,0.8123142,0.0004391864,0.0002812213,0.0003048092,0.0001228398,0.000008023106,0.1765002,0.00008791188,0.00004133929,0.000136423],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959854,0.001837937,0.000003575118,0.0006546191,0.0005912834,0.0008137585,0.00001492986,0.00001440566,0.00008404211],"genre_scores_gemma":[0.9991986,0.0002458403,0.00005648868,0.00002636161,0.0001072714,0.00003181753,0.000001393919,0.00005051515,0.000281688],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0900396,"threshold_uncertainty_score":0.9761912,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06501836203791858,"score_gpt":0.3765741373486722,"score_spread":0.3115557753107536,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}