{"id":"W2144800425","doi":"10.1210/jcem.86.12.8122","title":"Neuroactive Ring A-Reduced Metabolites of Progesterone in Human Plasma during Pregnancy: Elevated Levels of 5α-Dihydroprogesterone in Depressed Patients during the Latter Half of Pregnancy","year":2001,"lang":"en","type":"article","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Neuroendocrine regulation and behavior","field":"Psychology","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Pregnenolone; Endocrinology; Internal medicine; Metabolite; Pregnancy; Allopregnanolone; Neuroactive steroid; Pregnanolone; Gestation; Follicular phase; Medicine; Chemistry; Biology; Steroid; Hormone; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001779157,0.0002298676,0.0003167967,0.0005856103,0.0003540956,0.0004714644,0.0001375868,0.0004153021,0.0005532878],"category_scores_gemma":[0.0009395065,0.0002665277,0.0001333461,0.0004726604,0.0002590246,0.0001694555,0.0001585473,0.0004459282,0.0002177494],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002182358,"about_ca_system_score_gemma":0.0001607312,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001629037,"about_ca_topic_score_gemma":0.001476741,"domain_scores_codex":[0.9998565,0.00004092455,0.00001427779,0.00003191292,0.00003838856,0.00001799795],"domain_scores_gemma":[0.99978,0.00006015805,0.00006646873,0.00001679524,0.00002325632,0.00005325867],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.006668145,0.0001748204,0.8871195,0.000116785,0.0002101457,0.005065,0.001391933,0.0002064974,0.07222331,0.00008449941,0.0003333308,0.02640607],"study_design_scores_gemma":[0.00004598891,0.0008024406,0.9886087,0.00001200634,0.00005927028,0.004599959,0.000320745,0.0002306471,0.004629756,0.00005773573,0.0006242808,0.000008370323],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974354,0.001431727,0.0001561318,0.00004940158,0.00001112587,0.0000130975,0.0001464255,0.000009852907,0.0007466901],"genre_scores_gemma":[0.99906,0.0004490689,0.0001289748,0.00003897619,0.0000112158,0.0000106642,0.0001068164,0.000001346354,0.0001928999],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001629037,"threshold_uncertainty_score":0.003239155,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06501836203791858,"score_gpt":0.3765741373486722,"score_spread":0.3115557753107536,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}