{"id":"W2144820933","doi":"10.1158/0008-5472.can-06-0143","title":"Genetic Bases of Estrogen-Induced Tumorigenesis in the Rat: Mapping of Loci Controlling Susceptibility to Mammary Cancer in a Brown Norway × ACI Intercross","year":2006,"lang":"en","type":"article","venue":"Cancer Research","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"National Center for Research Resources; National Cancer Institute","keywords":"Cancer; Breast cancer; Biology; Carcinogenesis; Mammary tumor; Mammary gland; Estrogen; Phenotype; Population; Internal medicine; Endocrinology; Genetics; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001025619,0.0001475934,0.0002781417,0.0001940862,0.00005584685,0.00002072436,0.0004663397,0.0001576015,0.00002169018],"category_scores_gemma":[0.0001060526,0.0001154603,0.0001002601,0.0006816086,0.0001508253,0.000005976366,0.0001574847,0.0002943348,0.000002065517],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001080989,"about_ca_system_score_gemma":0.0004118244,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006779522,"about_ca_topic_score_gemma":0.004041282,"domain_scores_codex":[0.9979399,0.0004334232,0.0004177618,0.000403939,0.0003212231,0.0004836901],"domain_scores_gemma":[0.999113,0.00009380277,0.00007130318,0.0004438637,0.0002171704,0.00006091036],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003162861,0.0001110584,0.05807367,0.0001049113,0.00002629719,0.00001831372,0.0002730346,0.001649469,0.9362627,0.0000210606,0.0001826718,0.002960518],"study_design_scores_gemma":[0.001010318,0.0003064798,0.05371772,0.0001547663,0.000007315583,0.000003669229,0.0003243034,0.0001384414,0.9437374,0.00003833883,0.0004222655,0.0001389414],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911215,0.00757205,0.0000958189,0.0002875571,0.00007766156,0.0006987855,0.00003048601,0.000002787595,0.0001133038],"genre_scores_gemma":[0.9987203,0.0006078973,0.00009449432,0.00004290799,0.0001495215,0.0002791908,0.000009250763,0.0000179844,0.00007849126],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007598713,"threshold_uncertainty_score":0.9998344,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02991168707587455,"score_gpt":0.3451890731251003,"score_spread":0.3152773860492257,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}