{"id":"W2144824933","doi":"10.1101/gr.192278.115","title":"The landscape of genomic imprinting across diverse adult human tissues","year":2015,"lang":"en","type":"article","venue":"Genome Research","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":239,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Common Fund; National Institute of Biomedical Imaging and Bioengineering; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Cancer Institute; National Human Genome Research Institute; University of Miami; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Orionin Tutkimussäätiö; Université de Genève; National Institute of Mental Health; National Heart, Lung, and Blood Institute; Emil Aaltosen Säätiö; Israel Science Foundation; U.S. Public Health Service; Suomen Kulttuurirahasto; Roswell Park Cancer Institute; Hewlett-Packard Development Company; German-Israeli Foundation for Scientific Research and Development; Broad Institute; University of North Carolina; NIH Office of the Director; Van Andel Research Institute; National Institute on Drug Abuse; Science Applications International Corporation; University of Oxford; University of Chicago; Harvard University","keywords":"Imprinting (psychology); Genomic imprinting; Biology; Genetics; Gene; Allele; Gene expression; Gene expression profiling; DNA methylation","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001655284,0.00009470089,0.0001151157,0.00003686409,0.0003730592,0.00006917608,0.0005092758,0.00008621451,0.0000332481],"category_scores_gemma":[0.0002153933,0.00007256843,0.00006280274,0.0001179943,0.0002128126,0.000001832838,0.0009399526,0.0001549992,0.00006656055],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001426096,"about_ca_system_score_gemma":0.00008929933,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002228096,"about_ca_topic_score_gemma":0.00009804975,"domain_scores_codex":[0.998494,0.0001257982,0.00022264,0.0002730805,0.0003242697,0.0005602168],"domain_scores_gemma":[0.9987882,0.00002519956,0.00006434773,0.000499955,0.0004917771,0.0001305233],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00001442226,0.00002475901,0.02234703,0.00002204122,0.00004541693,0.000001861284,0.0006629752,0.000031606,0.9645222,0.0000851148,0.0005949889,0.01164759],"study_design_scores_gemma":[0.002799117,0.002400094,0.4560671,0.00004087311,0.00002035965,0.00008931131,0.03799484,0.0001921453,0.2865324,0.000608827,0.212568,0.0006868992],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941081,0.001433131,0.00003084584,0.0001055352,0.00006993364,0.0001735353,0.000008198305,0.000005692143,0.004065034],"genre_scores_gemma":[0.9969279,0.0002778912,0.0002349708,0.000009182949,0.0002331709,0.00001424928,0.0000180807,0.00001848604,0.002266106],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6779898,"threshold_uncertainty_score":0.2959255,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06576906099941318,"score_gpt":0.3781386964029783,"score_spread":0.3123696354035651,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}