{"id":"W2144824933","doi":"10.1101/gr.192278.115","title":"The landscape of genomic imprinting across diverse adult human tissues","year":2015,"lang":"en","type":"article","venue":"Genome Research","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":239,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Common Fund; National Institute of Biomedical Imaging and Bioengineering; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Cancer Institute; National Human Genome Research Institute; University of Miami; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Orionin Tutkimussäätiö; Université de Genève; National Institute of Mental Health; National Heart, Lung, and Blood Institute; Emil Aaltosen Säätiö; Israel Science Foundation; U.S. Public Health Service; Suomen Kulttuurirahasto; Roswell Park Cancer Institute; Hewlett-Packard Development Company; German-Israeli Foundation for Scientific Research and Development; Broad Institute; University of North Carolina; NIH Office of the Director; Van Andel Research Institute; National Institute on Drug Abuse; Science Applications International Corporation; University of Oxford; University of Chicago; Harvard University","keywords":"Imprinting (psychology); Genomic imprinting; Biology; Genetics; Gene; Allele; Gene expression; Gene expression profiling; DNA methylation","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001454756,0.0001098205,0.0002261011,0.0006685577,0.0001230266,0.0003517222,0.0001105168,0.0001042156,0.0009535199],"category_scores_gemma":[0.0003947321,0.0001264964,0.00009167381,0.0006064305,0.0002194977,0.0001247573,0.0002394078,0.0001322,0.0001825185],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000112463,"about_ca_system_score_gemma":0.00008194597,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006805307,"about_ca_topic_score_gemma":0.0009788106,"domain_scores_codex":[0.9998478,0.0000290038,0.00001052328,0.00006036455,0.00003086703,0.00002147804],"domain_scores_gemma":[0.9997345,0.000102561,0.00007898561,0.00003631248,0.00002369392,0.00002393827],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004976225,0.00001529816,0.188905,0.0001300234,0.0002071045,0.0006989451,0.0004365435,0.0005095871,0.754724,0.000428658,0.0002026762,0.0532445],"study_design_scores_gemma":[0.000005938782,0.0001045174,0.9635338,0.000009197376,0.00006438515,0.001726346,0.0001166209,0.0003400522,0.03163999,0.000532107,0.00191854,0.000008551487],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938762,0.002586186,0.001603286,0.00003558811,0.00000211306,0.000004626784,0.0007644091,0.00003024529,0.001097364],"genre_scores_gemma":[0.9975374,0.0008416066,0.0006829677,0.00003201739,0.000005816593,0.000007197002,0.0005012224,0.00001571412,0.0003760999],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009535199,"threshold_uncertainty_score":0.003189862,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06576906099941318,"score_gpt":0.3781386964029783,"score_spread":0.3123696354035651,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}